000 03863nam a22005415i 4500
001 978-94-007-6088-2
003 DE-He213
005 20140220082940.0
007 cr nn 008mamaa
008 130202s2013 ne | s |||| 0|eng d
020 _a9789400760882
_9978-94-007-6088-2
024 7 _a10.1007/978-94-007-6088-2
_2doi
050 4 _aQR1-502
072 7 _aPSG
_2bicssc
072 7 _aTCB
_2bicssc
072 7 _aSCI010000
_2bisacsh
072 7 _aSCI045000
_2bisacsh
082 0 4 _a660.62
_223
100 1 _aChakraborty, Ranjan.
_eeditor.
245 1 0 _aIron Uptake in Bacteria with Emphasis on E. coli and Pseudomonas
_h[electronic resource] /
_cedited by Ranjan Chakraborty, Volkmar Braun, Klaus Hantke, Pierre Cornelis.
264 1 _aDordrecht :
_bSpringer Netherlands :
_bImprint: Springer,
_c2013.
300 _aXI, 89 p. 17 illus., 14 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringerBriefs in Molecular Science,
_x2191-5407
505 0 _aFerric Siderophore Transport via Outer Membrane Receptors of Escherichia coli: Structural Advancement and a Tribute to Dr. Dick van der Helm- an ‘Ironman’ of Siderophore Biology -- The Tricky Ways Bacteria Cope with Iron Limitation -- Iron Transport Systems and Iron Homeostasis in Pseudomonas.
520 _aIron is essential for the growth of most bacteria because it serves as a cofactor for vital enzymes and for the components of the electron transport chain. Moreover, Iron plays an important role in bacterial pathogenicity; in fact, the iron transport systems in bacteria works as target for designing novel antibiotics. Because iron is not soluble under aerobic conditions, bacteria have had to find ways to overcome iron deficiency. One of them is producing an iron-chelating small organic molecule called siderophore. Indeed, most bacteria and fungi produce structurally and chemically diverse siderophores which are transported back to the cytoplasm using complex energy dependent transport systems. Escherichia coli and Pseudomonas were the first ones to be tested; however, nowadays iron transport systems have been investigated in many other bacteria. Iron Uptake in Bacteria with Emphasis on E. coli and Pseudomonas reviews the recent advancements in the field of iron transport systems in bacteria. Chapter 1 is dedicated to Dr. Dick van der Helm’s contribution to the field of siderophore biology. It then describes and discusses the structural advances in the components and the mechanism of siderophore mediated iron transport systems in E.coli. Chapter 2 details the variety of iron transport and iron regulatory systems of both gram negative and gram positive bacteria. Finally, chapter 3 describes the iron transport systems of Pseudomonas. This book is aimed at researchers in the fields of iron metabolism in multiple organisms, and to those who are interested in studying iron transport systems of bacteria. It appeals also to scientists researching structure and function relationship of proteins.
650 0 _aChemistry.
650 0 _aMedicine.
650 0 _aMicrobiology.
650 0 _aBiochemistry.
650 1 4 _aChemistry.
650 2 4 _aApplied Microbiology.
650 2 4 _aBiochemistry, general.
650 2 4 _aMolecular Medicine.
700 1 _aBraun, Volkmar.
_eeditor.
700 1 _aHantke, Klaus.
_eeditor.
700 1 _aCornelis, Pierre.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9789400760875
830 0 _aSpringerBriefs in Molecular Science,
_x2191-5407
856 4 0 _uhttp://dx.doi.org/10.1007/978-94-007-6088-2
912 _aZDB-2-CMS
999 _c99805
_d99805