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001 978-94-007-5811-7
003 DE-He213
005 20140220082939.0
007 cr nn 008mamaa
008 130125s2013 ne | s |||| 0|eng d
020 _a9789400758117
_9978-94-007-5811-7
024 7 _a10.1007/978-94-007-5811-7
_2doi
050 4 _aQH324.2-324.25
072 7 _aPSD
_2bicssc
072 7 _aUB
_2bicssc
072 7 _aSCI056000
_2bisacsh
082 0 4 _a570.285
_223
100 1 _aWang, Xiangdong.
_eeditor.
245 1 0 _aBioinformatics of Human Proteomics
_h[electronic resource] /
_cedited by Xiangdong Wang.
264 1 _aDordrecht :
_bSpringer Netherlands :
_bImprint: Springer,
_c2013.
300 _aXIII, 390 p. 121 illus., 100 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aTranslational Bioinformatics,
_x2213-2775 ;
_v3
505 0 _aClinical Bioinformatics in Human Proteomics Research -- Proteomics defines protein interaction -- Protein Function Microarrays: Design, Use and Bioinformatic Analysis in Cancer Biomarker Discovery and Quantitation -- Proteomics and Cancer Research -- Towards development of novel peptide-based cancer therapeutics: computational design and experimental evaluation -- Advances of proteomic methods -- Clinical and Biomedical Mass Spectrometry – New Frontiers in Drug Developments and Diagnosis -- Disease biomarkers: Modeling MR spectroscopy and clinical applications -- Processing of mass spectrometry data in clinical applications -- Bioinformatics approach for finding target protein in infectious disease -- Identification of network biomarkers for cancer diagnosis -- Software development for quantitative proteomics using stable isotope labeling -- Clinical translation of protein biomarkers integrated with bioinformatics -- Proteomic approaches for urine biomarker discovery in bladder cancer -- Antibody microarray and multiplexing.-Proteomics in Anaesthesia and Intensive Care Medicine.
520 _a“Bioinformatics of Human Proteomics” discusses the development of methods, techniques and applications in the field of protein bioinformatics, an important direction in bioinformatics. It collects contributions from expert researchers in order to provide a practical guide to this complex field of study. The book covers the protein interaction network, drug discovery and development, the relationship between translational medicine and bioinformatics, and advances in proteomic methods, while also demonstrating important bioinformatics tools and methods available today for protein analysis, interpretation and predication. It is intended for experts or senior researchers in the fields of clinical research-related biostatistics, bioinformatics, computational biology, medicine, statistics, system biology, molecular diagnostics, biomarkers, or drug discovery and development. Dr. Xiangdong Wang works as a distinguished professor of Respiratory Medicine at Fudan University, Shanghai, China. He serves as Director of Biomedical Research Center, Fudan University Zhongshan Hospital and adjunct professor of Clinical Bioinformatics at Lund University, Sweden. His main research is focused on the role of clinical bioinformatics in the development of disease-specific biomarkers and dynamic network biomarkers, the molecular mechanism of organ dysfunction and potential therapies.      
650 0 _aLife sciences.
650 0 _aMedicine.
650 0 _aBioinformatics.
650 0 _aProteomics.
650 0 _aBiological models.
650 1 4 _aLife Sciences.
650 2 4 _aBioinformatics.
650 2 4 _aComputational Biology/Bioinformatics.
650 2 4 _aMolecular Medicine.
650 2 4 _aProteomics.
650 2 4 _aSystems Biology.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9789400758100
830 0 _aTranslational Bioinformatics,
_x2213-2775 ;
_v3
856 4 0 _uhttp://dx.doi.org/10.1007/978-94-007-5811-7
912 _aZDB-2-SBL
999 _c99723
_d99723