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001 978-94-007-5787-5
003 DE-He213
005 20140220082939.0
007 cr nn 008mamaa
008 130321s2013 ne | s |||| 0|eng d
020 _a9789400757875
_9978-94-007-5787-5
024 7 _a10.1007/978-94-007-5787-5
_2doi
050 4 _aQH573-671
072 7 _aPSF
_2bicssc
072 7 _aSCI017000
_2bisacsh
072 7 _aSCI049000
_2bisacsh
082 0 4 _a571.9453
_223
100 1 _aJakob, Ursula.
_eeditor.
245 1 0 _aOxidative Stress and Redox Regulation
_h[electronic resource] /
_cedited by Ursula Jakob, Dana Reichmann.
264 1 _aDordrecht :
_bSpringer Netherlands :
_bImprint: Springer,
_c2013.
300 _aX, 483 p. 72 illus., 44 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aChapter 1 The Chemistry of Thiol Oxidation and Detection -- Chapter 2 Radical Scavenging by Thiols and the Fate of Thiyl Radicals -- Chapter 3 Redox Homeostasis -- Chapter 4 Sulfenic Acids and Peroxiredoxins in Oxidant Defense and Signaling -- Chapter 5  Fluorescent imaging of redox species in multicellular organisms -- Chapter 6 Redox Proteomics -- Chapter 7 Computational redox biology: methods and applications -- Chapter 8  Redox regulation in plants: Glutathione and “Redoxin” related families -- Chapter 9  Prokaryotic Redox Switches -- Chapter 10   Combating Oxidative/Nitrosative Stress with Electrophilic Counterattack Strategies -- Chapter 11 Reactive Oxygen Species, Kinase Signaling, and Redox Regulation of Epigenetics -- Chapter 12 Redox regulation of stem cell function -- Chapter 13 Oxidative Stress in Infectious Diseases -- Chapter 14 Oxidative Stress in Aging -- Chapter 15 Oxidative Stress in Cancer -- Chapter 16 Redox Pathways as a Platform in Drug Development.
520 _aMany physiological conditions such as host defense or aging and pathological conditions such as neurodegenerative diseases, and diabetes are associated with the accumulation of high levels of reactive oxygen species and reactive nitrogen species. This generates a condition called oxidative stress. Low levels of reactive oxygen species, however, which are continuously produced during aerobic metabolism, function as important signaling molecules, setting the metabolic pace of cells and regulating processes ranging from gene expression to apoptosis. For this book we would like to recruit the experts in the field of redox chemistry, bioinformatics and proteomics, redox signaling and oxidative stress biology to discuss how organisms achieve the appropriate redox balance, the mechanisms that lead to oxidative stress conditions and the physiological consequences that contribute to aging and disease.
650 0 _aLife sciences.
650 0 _aBiochemistry.
650 0 _aPost-translational modification of proteins.
650 0 _aBiological models.
650 0 _aCytology.
650 1 4 _aLife Sciences.
650 2 4 _aOxidative Stress.
650 2 4 _aMedical Biochemistry.
650 2 4 _aCell Physiology.
650 2 4 _aPosttranslational Modification.
650 2 4 _aCell Physiology.
650 2 4 _aSystems Biology.
700 1 _aReichmann, Dana.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9789400757868
856 4 0 _uhttp://dx.doi.org/10.1007/978-94-007-5787-5
912 _aZDB-2-SBL
999 _c99717
_d99717