000 03776nam a22005295i 4500
001 978-94-007-4923-8
003 DE-He213
005 20140220082935.0
007 cr nn 008mamaa
008 121204s2013 ne | s |||| 0|eng d
020 _a9789400749238
_9978-94-007-4923-8
024 7 _a10.1007/978-94-007-4923-8
_2doi
050 4 _aQH505
072 7 _aPHVN
_2bicssc
072 7 _aPHVD
_2bicssc
072 7 _aSCI009000
_2bisacsh
082 0 4 _a571.4
_223
100 1 _aPuglisi, Joseph D.
_eeditor.
245 1 0 _aBiophysics and Structure to Counter Threats and Challenges
_h[electronic resource] /
_cedited by Joseph D. Puglisi, Manolia V. Margaris.
264 1 _aDordrecht :
_bSpringer Netherlands :
_bImprint: Springer,
_c2013.
300 _aX, 169 p. 68 illus.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aNATO Science for Peace and Security Series B: Physics and Biophysics,
_x1874-6500
505 0 _aFrom the Contents: Macromolecular Models by Single Molecule FRET -- System-specific  scoring Functions; Application to Guanine-containing Ligands and Thrombin -- Large DNA Template Dependent Error Variation during Transcription -- Structures of Novel HIV-inactivating Lectins -- Fluorescence Resonance Energy Transfer Studies of Structure and Dynamics in Nucleic Acids -- An Introduction to Macromolecular Crystallography through Parable and Analogy -- Using NMR to determine the Conformation of the HIV reverse Transcription Initiation Complex -- Approaches to Protein-ligand Structure Determination by NMR Spectroscopy: Applications in Drug Binding to the Cardiac Regulatory Protein Troponin C -- How do Nascent Proteins emerge from the Ribosome? -- Course Abstracts and Posters -- Author Index.
520 _aThis ASI brought together a diverse group of experts who span virology, biology, biophysics, chemistry, physics and engineering.  Prominent lecturers representing world renowned scientists from nine (9) different countries, and students from around the world representing eighteen (18) countries, participated in the ASI organized by Professors Joseph Puglisi (Stanford University, USA) and Alexander Arseniev (Moscow, RU).   The central hypothesis underlying this ASI was that interdisciplinary research, merging principles of physics, chemistry and biology, can drive new discovery in detecting and fighting chemical and bioterrorism agents, lead to cleaner environments and improved energy sources, and help propel development in NATO partner countries.  At the end of the ASI students had an appreciation of how to apply each technique to their own particular research problem and to demonstrate that multifaceted approaches and new technologies are needed to solve the biological challenges of our time.  The course succeeded in training a new generation of biologists and chemists who will probe the molecular basis for life and disease.
650 0 _aPhysics.
650 0 _aBiotechnology.
650 0 _aChemistry.
650 0 _aCrystallography.
650 1 4 _aPhysics.
650 2 4 _aBiophysics and Biological Physics.
650 2 4 _aSolid State Physics.
650 2 4 _aCrystallography.
650 2 4 _aBiotechnology.
650 2 4 _aTheoretical and Computational Chemistry.
700 1 _aMargaris, Manolia V.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9789400749221
830 0 _aNATO Science for Peace and Security Series B: Physics and Biophysics,
_x1874-6500
856 4 0 _uhttp://dx.doi.org/10.1007/978-94-007-4923-8
912 _aZDB-2-PHA
999 _c99499
_d99499