000			03575nam a22004695i 4500
001			978-3-7091-1175-8
003			DE-He213
005			20140220082925.0
007			cr nn 008mamaa
008			130130s2013 au | s |||| 0|eng d
020			_a9783709111758 _9978-3-7091-1175-8
024	7		_a10.1007/978-3-7091-1175-8 _2doi
050		4	_aRC346-429.2
072		7	_aMJN _2bicssc
072		7	_aMED056000 _2bisacsh
082	0	4	_a616.8 _223
100	1		_aJolkkonen, Jukka. _eeditor.
245	1	0	_aCell-Based Therapies in Stroke _h[electronic resource] / _cedited by Jukka Jolkkonen, Piotr Walczak.
264		1	_aVienna : _bSpringer Vienna : _bImprint: Springer, _c2013.
300			_aVIII, 204 p. 24 illus., 20 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aPreclinical Optimization of Cell Therapies: Cell Therapy and Structural Plasticity Following Cerebral Ischemia.- Delivery Routes for Cell Therapy in Stroke -- Different Sources of Stem Cells for Transplantation Therapy in Stroke -- Efficacy of Transplant and Endogenous Precursor and Stem Cell Interventions on Stroke Recovery -- Translational Imaging Techniques to Study Cell Therapy: Cell Labeling Methods for Non-Invasive MR Imaging of Stem Cells -- Strategies for Enhanced, MRI-guided Targeting of Stem Cells to Stroke Lesions -- Image-guided Injection and Non-invasive Monitoring of Tissue Regeneration in the Stroke-damaged Brain -- Tracking of Autologous VSOP-Labelled Mesenchymal Stem Cells in the Sheep Brain Using 3T MRI -- Neural Stem Cell Mapping With High Resolution Rapid Scanning X-ray Fluorescence Imaging -- In Vivo Biodistribution Studies and Cell Tracking in Stroke Using SPECT Imaging -- Early Phase Clinical Studies: Clinical Trials -- Intravenous Cell Therapies for Stroke -- Intra-arterial Cell Therapy in Stroke Patients -- Intraventricular Route of Cell Transplantation for Stroke-Related Diseases.
520			_aStroke remains one of the main causes of death and disability worldwide. Effective therapy for stroke recovery remains an unmet need. Much hope and promises are placed on cell-based therapies. The aim of this book is to provide focused yet comprehensive reviews on the current state of cell-based approaches in the treatment of stroke. The topics covered include experimental data on functional outcome after intravascular and intracerebral delivery of cells in stroke animals, followed by translational chapters which will rely heavily on the use of different imaging modalities in the tracking of cells. The last and most challenging part will describe the early phase of clinical studies, providing guidelines for future research and clinical applications. Clearly and concisely written, this text will be a useful resource for neurologists, radiologists, and neuroscientists interested in cell transplantation as a therapeutic strategy for stroke patients.
650		0	_aMedicine.
650		0	_aNeurosciences.
650		0	_aRadiology, Medical.
650		0	_aNeurology.
650	1	4	_aMedicine & Public Health.
650	2	4	_aNeurology.
650	2	4	_aImaging / Radiology.
650	2	4	_aNeurosciences.
700	1		_aWalczak, Piotr. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783709111741
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-7091-1175-8
912			_aZDB-2-SME
999			_c98963 _d98963