000 03514nam a22005415i 4500
001 978-3-642-36340-5
003 DE-He213
005 20140220082904.0
007 cr nn 008mamaa
008 130228s2013 gw | s |||| 0|eng d
020 _a9783642363405
_9978-3-642-36340-5
024 7 _a10.1007/978-3-642-36340-5
_2doi
050 4 _aQR46
072 7 _aMMFM
_2bicssc
072 7 _aMED052000
_2bisacsh
082 0 4 _a616.9041
_223
100 1 _aChhatwal, G. Singh.
_eeditor.
245 1 0 _aHost-Pathogen Interactions in Streptococcal Diseases
_h[electronic resource] /
_cedited by G. Singh Chhatwal.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2013.
300 _aVIII, 255 p. 17 illus., 11 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aCurrent Topics in Microbiology and Immunology,
_x0070-217X ;
_v368
505 0 _aGroup A Streptococcal Diseases and Their Global Burden -- Molecular Markers for the Study of Streptococcal Epidemiology -- Epidemiology and Pathogenicity of Zoonotic Streptococci -- Adherence and Invasion of Streptococci to Eukaryotic Cells and Their Role in Disease Pathogenesis -- Common Regulators of Virulence in Streptococci -- Host-Pathogen Interactions in Streptococcal Immune Sequelae -- Immunopathogenesis of Streptococcal Deep Tissue Infections -- Modulation of the Coagulation System During Severe Streptococcal Disease -- Group A Streptococcal Vaccine Candidates: Potential for the Development of a Human Vaccine -- Clinical Management of the Most Common Group A β-Hemolytic Streptococcal Infections.
520 _aStreptococci are Gram-positive bacteria that cause a wide spectrum of diseases, such as pharyngitis, necrotizing fasciitis and streptococcal toxic shock syndrome, as well as rheumatic fever and rheumatic heart disease as sequelae. Antibiotics alone have not been able to control the disease and in spite of many efforts an effective vaccine is not yet available. A prerequisite for novel and successful strategies for combating these bacteria is a complete understanding of the highly complex pathogenic mechanisms involved, which are analyzed in this volume. In ten chapters, prominent authors cover various aspects including streptococcal diseases and global burden, epidemiology, adaptation and transmission, and molecular mechanisms of different diseases, as well as sequelae, vaccine development and clinical management. This book will serve as a valuable reference work for scientists, students, clinicians and public health workers and provide new approaches to meeting the challenge of streptococcal diseases.
650 0 _aMedicine.
650 0 _aImmunology.
650 0 _aMicrobiology.
650 0 _aVaccines.
650 0 _aPublic health.
650 0 _aBacteriology.
650 1 4 _aBiomedicine.
650 2 4 _aMedical Microbiology.
650 2 4 _aImmunology.
650 2 4 _aVaccine.
650 2 4 _aMolecular Medicine.
650 2 4 _aPublic Health.
650 2 4 _aBacteriology.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642363399
830 0 _aCurrent Topics in Microbiology and Immunology,
_x0070-217X ;
_v368
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-36340-5
912 _aZDB-2-SBL
999 _c97849
_d97849