000			03734nam a22006015i 4500
001			978-3-642-36229-3
003			DE-He213
005			20140220082903.0
007			cr nn 008mamaa
008			130708s2013 gw | s |||| 0|eng d
020			_a9783642362293 _9978-3-642-36229-3
024	7		_a10.1007/978-3-642-36229-3 _2doi
050		4	_aRB45
072		7	_aMJF _2bicssc
072		7	_aMED038000 _2bisacsh
082	0	4	_a616.15 _223
100	1		_aDeeg, H. Joachim. _eauthor.
245	1	0	_aMyelodysplastic Syndromes _h[electronic resource] / _cby H. Joachim Deeg, David T. Bowen, Steven D. Gore, Torsten Haferlach, Michelle M. Le Beau, Charlotte Niemeyer.
250			_a2nd ed. 2013.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg : _bImprint: Springer, _c2013.
300			_aVIII, 245 p. 42 illus., 29 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aHematologic Malignancies
505	0		_aClincial Presentation and Differential Diagnosis -- Epidemiology and Etiology -- Cytogenetic Diagnosis of Myelodysplastic Syndromes -- MDS Stem Cell  Biology -- The Biology of Myelodysplastic Syndrome Associated with Isolated del(5q) -- Other -- Overlap with MPN -- Classification and Staging of Myelodysplastic Syndromes -- Immunophenotyping in Myelodysplastic Syndrome -- Prognostic Models for Patients with Myelodysplastic Syndromes -- Low Risk MDS -- Management of High-Risk Myelodysplastic Syndrome -- Hematopoietic Cell Transplantation -- MDS in Children.
520			_aMyelodysplastic syndromes (MDS) have been studied intensively in recent years and knowledge of the disease process and underlying molecular defects in MDS has expanded rapidly.  With the aging of populations and the concurrent increase in the diagnosis of MDS, these findings are of central clinical importance. New prognostic classification systems with refined prognostic significance have been developed, and molecular abnormalities are now finding their way into the process of clinical decision-making. The book has been  completely updated since the first edition and concisely summarizes the state of the art on all aspects of MDS, including clinical presentation, etiology, epidemiology, molecular biology, classification, and staging. The different chapters provide  guidance on diagnosis and differential diagnosis, as well as on treatment strategies, including the use of hematopoietic growth factors, biology-based treatment, hematopoietic stem cell transplantation, and supportive care. MDS in children is also addressed in a separate chapter. This practically oriented book will be a valuable resource for a broad range of students and practitioners in the field.
650		0	_aMedicine.
650		0	_aInternal medicine.
650		0	_aHematology.
650		0	_aOncology.
650		0	_aPathology.
650		0	_aTransplantation of organs, tissues, etc.
650	1	4	_aMedicine & Public Health.
650	2	4	_aHematology.
650	2	4	_aInternal Medicine.
650	2	4	_aOncology.
650	2	4	_aPathology.
650	2	4	_aTransplant Surgery.
700	1		_aBowen, David T. _eauthor.
700	1		_aGore, Steven D. _eauthor.
700	1		_aHaferlach, Torsten. _eauthor.
700	1		_aLe Beau, Michelle M. _eauthor.
700	1		_aNiemeyer, Charlotte. _eauthor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783642362286
830		0	_aHematologic Malignancies
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-642-36229-3
912			_aZDB-2-SME
999			_c97818 _d97818