000			03663nam a22005295i 4500
001			978-3-642-33430-6
003			DE-He213
005			20140220082855.0
007			cr nn 008mamaa
008			121215s2013 gw | s |||| 0|eng d
020			_a9783642334306 _9978-3-642-33430-6
024	7		_a10.1007/978-3-642-33430-6 _2doi
050		4	_aQH505
072		7	_aPHVN _2bicssc
072		7	_aPHVD _2bicssc
072		7	_aSCI009000 _2bisacsh
082	0	4	_a571.4 _223
100	1		_aSkulachev, Vladimir P. _eauthor.
245	1	0	_aPrinciples of Bioenergetics _h[electronic resource] / _cby Vladimir P. Skulachev, Alexander V. Bogachev, Felix O. Kasparinsky.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg : _bImprint: Springer, _c2013.
300			_aXVI, 436 p. 191 illus., 99 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aPart I: General Aspects of Bioenergetics: Introduction -- Part II: Generators of Proton Potential: Chlorophyll-Based Generators of Proton Potential -- Organotrophic Energetics -- The Respiratory Chain -- Structure of Respiratory Chains of Procaryotes and Mitochondria of Protozoa, Plants, and Fungi -- Bacteriorhodopsin -- Part III: Consumers -- Driven Chemical Work -- Driven Mechanical Work: Bacterial Motility -- Driven Osmotic Work.- Energy Source for Heat Production -- Part IV Interaction and Regulation of Proton Potential Generators and Consumers: Regulation, Transmission, and Buffering of Proton Potential -- Part V The Sodium World: Generators -- Part VI Mitochondrial Reactive Oxygen Species and Mechanisms of Aging: Concept of Aging as a Result of Programmed Slow Poisoning of Organism with Mitochondrial Reactive Oxygen Species -- Possible Medical Applications of Membrane Bioenergetics: Mitochondria-Targeted Antioxidants as Geroprotectors -- Appendices.          .
520			_aPrinciples of Bioenergetics summarizes one of the quickly growing branches of modern biochemistry. Bioenergetics concerns energy transductions occurring in living systems and this book pays special attention to molecular mechanisms of these processes. The main subject of the book is the "energy coupling membrane" which refers to inner membranes of intracellular organelles, for example, mitochondria and chloroplasts. Cellular cytoplasmic membranes where respiratory and photosynthetic energy transducers, as well as ion-transporting ATP-synthases (ATPases) are also part of this membrane. Significant attention is paid to the alternative function of mitochondria as generators of reactive oxygen species (ROS) that mediate programmed death of cells (apoptosis and necrosis) and organisms (phenoptosis). The latter process is considered as a key mechanism of aging which may be suppressed by mitochondria-targeted antioxidants.
650		0	_aPhysics.
650		0	_aChemistry, Physical organic.
650		0	_aBiochemistry.
650		0	_aGeriatrics.
650		0	_aCytology.
650	1	4	_aPhysics.
650	2	4	_aBiophysics and Biological Physics.
650	2	4	_aCell Biology.
650	2	4	_aPhysical Chemistry.
650	2	4	_aMedicinal Chemistry.
650	2	4	_aGeriatrics/Gerontology.
700	1		_aBogachev, Alexander V. _eauthor.
700	1		_aKasparinsky, Felix O. _eauthor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783642334290
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-642-33430-6
912			_aZDB-2-PHA
999			_c97378 _d97378