000 03009nam a22004695i 4500
001 978-3-319-00446-4
003 DE-He213
005 20140220082838.0
007 cr nn 008mamaa
008 130807s2013 gw | s |||| 0|eng d
020 _a9783319004464
_9978-3-319-00446-4
024 7 _a10.1007/978-3-319-00446-4
_2doi
050 4 _aQD380-388
072 7 _aPNNP
_2bicssc
072 7 _aTEC055000
_2bisacsh
082 0 4 _a541.2254
_223
100 1 _aKlinger, Daniel.
_eauthor.
245 1 0 _aLight-Sensitive Polymeric Nanoparticles Based on Photo-Cleavable Chromophores
_h[electronic resource] /
_cby Daniel Klinger.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2013.
300 _aXVII, 224 p. 108 illus., 21 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringer Theses, Recognizing Outstanding Ph.D. Research,
_x2190-5053
505 0 _aIntroduction -- Motivation -- Theoretical Part -- Outline -- Results and Discussion -- Conclusion and Outlook -- Experimental Part.
520 _aThe triggered release of functional compounds from such polymeric carriers as micelles, nanoparticles or nanogels is a rapidly developing and highly versatile concept which is expected to be one of the key approaches to future therapeutics. In his thesis, Daniel Klinger highlights the approach of stimuli-responsive microgels for such applications and discusses why especially light as a trigger has an outstanding position amongst the family of conventional stimuli. Based on these considerations, the author focuses on the design, synthesis and characterization of novel photo-sensitive microgels and nanoparticles as potential materials for the loading and light-triggered release/accessibility of functional compounds. Starting from the synthesis of photo-cleavable organic building blocks and their use in the preparation of polymeric nanoparticles, continuing to the examination of their loading and release profiles, and concluding with biological in vitro studies of the final materials, Daniel Klinger’s work is an excellent example of the multidisciplinary research needed for the successful development of new materials in this field and has led to a number of further publications in internationally respected journals.
650 0 _aChemistry.
650 0 _aPolymers.
650 0 _aNanotechnology.
650 1 4 _aChemistry.
650 2 4 _aPolymer Sciences.
650 2 4 _aNanotechnology.
650 2 4 _aNanoscale Science and Technology.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319004457
830 0 _aSpringer Theses, Recognizing Outstanding Ph.D. Research,
_x2190-5053
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-319-00446-4
912 _aZDB-2-CMS
999 _c96430
_d96430