000 02673nam a22004575i 4500
001 978-1-4614-7651-1
003 DE-He213
005 20140220082830.0
007 cr nn 008mamaa
008 130724s2013 xxu| s |||| 0|eng d
020 _a9781461476511
_9978-1-4614-7651-1
024 7 _a10.1007/978-1-4614-7651-1
_2doi
050 4 _aR-RZ
072 7 _aMBGR
_2bicssc
072 7 _aMED000000
_2bisacsh
082 0 4 _a610
_223
100 1 _aPöhlmann, Stefan.
_eeditor.
245 1 0 _aViral Entry into Host Cells
_h[electronic resource] /
_cedited by Stefan Pöhlmann, Graham Simmons.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2013.
300 _aXVII, 199 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v790
505 0 _aAttachment Factors -- Picornavirus Entry -- Reovirus Receptors, Cell Entry, and Proapoptotic Signaling -- Entry of Influenza Virus -- Filovirus Entry -- Paramyxovirus Entry -- Cellular entry of retroviruses -- Class II Fusion Proteins -- Entry of Rhabdoviruses into Animal Cells -- Entry of Herpesviruses into Cells: The Enigma Variations.
520 _aFor a virus to invade a host cell it needs to penetrate the physical barrier imposed by the plasma membrane. Viruses have evolved specialized surface proteins to meet this challenge. These proteins facilitate delivery of the viral genetic information into the host cell by either fusing the viral envelope with a host cell membrane or by forming membrane pores. Membrane fusion and pore formation critically depend on the engagement of host cell receptors and receptor choice is a key determinant of viral tropism. The multi-faceted interplay between viral and cellular factors during virus entry is a fascinating field of study, which can provide important insight into viral pathogenesis and define new targets for intervention. This book provides a comprehensive overview of this exciting field of research.
650 0 _aMedicine.
650 0 _aCytology.
650 1 4 _aBiomedicine.
650 2 4 _aBiomedicine general.
650 2 4 _aCell Biology.
700 1 _aSimmons, Graham.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461476504
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v790
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-7651-1
912 _aZDB-2-SBL
999 _c95956
_d95956