000			03138nam a22004815i 4500
001			978-1-4614-7351-0
003			DE-He213
005			20140220082829.0
007			cr nn 008mamaa
008			131011s2013 xxu| s |||| 0|eng d
020			_a9781461473510 _9978-1-4614-7351-0
024	7		_a10.1007/978-1-4614-7351-0 _2doi
050		4	_aQR180-189.5
072		7	_aMJCM _2bicssc
072		7	_aMED044000 _2bisacsh
082	0	4	_a616.079 _223
100	1		_aRogers, Thomas J. _eeditor.
245	1	0	_aSmoking and Lung Inflammation _h[electronic resource] : _bBasic, Pre-Clinical and Clinical Research Advances / _cedited by Thomas J. Rogers, Gerard J. Criner, William D. Cornwell.
264		1	_aNew York, NY : _bSpringer New York : _bImprint: Springer, _c2013.
300			_aVII, 213 p. 21 illus., 19 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aIntroduction -- Immunopathology of COPD -- Monocyte Populations Which Participate in Chronic Lung Inflammation -- Neutrophils Inflammation in COPD -- Role of Epithelial Cells in Chronic Inflammatory Lung Disease -- The Relationship Between Oxidative Stress Responses and Lung Inflammation with Cigarette Smoking -- Autoimmune Mechanisms Contributing to Chronic Obstructive Pulmonary Disease -- Chronic Obstructive Pulmonary Disease (COPD): Local and Systemic Disease -- Infectious Mechanisms Regulating Susceptibility to Acute Exacerbations of COPD -- COPD: Biomarkers and Phenotypes -- Anti-inflammatory Therapeutics in COPD: Past, Present and Future.
520			_aSmoking and Lung Inflammation is the first book directly related to chronic lung inflammation of its kind in several respects. First, the it focuses on both basic and clinical research on COPD, and the inflammatory mechanisms that function in these diseases. Second, it is unique with respect to scope of the discussion of the unusual characteristics of the immune response which occurs in these patients. Third, it includes knowledge being gained from translational research conducted through clinical trials at several Medical Schools in the United States. Not only is this research providing information about novel drugs and therapies, but it is also advancing our understanding of the genetics of these diseases. This work will illuminate the molecular basis for these diseases, and hopefully will permit us to individualize the therapies for these diseases.
650		0	_aMedicine.
650		0	_aImmunology.
650		0	_aPneumology.
650		0	_aPathology.
650	1	4	_aBiomedicine.
650	2	4	_aImmunology.
650	2	4	_aPneumology/Respiratory System.
650	2	4	_aPathology.
700	1		_aCriner, Gerard J. _eeditor.
700	1		_aCornwell, William D. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781461473503
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-4614-7351-0
912			_aZDB-2-SBL
999			_c95905 _d95905