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001 978-1-4614-5966-8
003 DE-He213
005 20140220082822.0
007 cr nn 008mamaa
008 130125s2013 xxu| s |||| 0|eng d
020 _a9781461459668
_9978-1-4614-5966-8
024 7 _a10.1007/978-1-4614-5966-8
_2doi
050 4 _aQH505
072 7 _aPHVN
_2bicssc
072 7 _aPHVD
_2bicssc
072 7 _aSCI009000
_2bisacsh
082 0 4 _a571.4
_223
100 1 _aThiriet, Marc.
_eauthor.
245 1 0 _aTissue Functioning and Remodeling in the Circulatory and Ventilatory Systems
_h[electronic resource] /
_cby Marc Thiriet.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2013.
300 _aXXI, 962 p. 72 illus., 3 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aBiomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems,
_x2193-1682 ;
_v5
505 0 _aPreface -- Chapter 1: Blood -- Chapter 2: Hematopoiesis -- Chapter 3: Blood Cells -- Chapter 4: Lymph Drainage -- Chapter 5: Cardiomyocytes -- Chapter 6: Heart Wall -- Chapter 7: Vessel Wall -- Chapter 8: Smooth Myocytes -- Chapter 9: Vascular Endothelium -- Chapter 10: Vascular Growth -- Chapter 11: Tissue Development, Repair, and Remodeling -- Chapter 12: Airway Surface Liquid and Respiratory Mucus -- Chapter 13: Surfactant -- Chapter 14: Conclusion -- References -- List of Currently Used Prefixes and Suffixes -- List of Aliases -- Complementary Lists of Notations -- Index.
520 _aThe volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. Volume 5 is devoted to cells, tissues, and organs of the cardiovascular and ventilatory systems with an emphasis on mechanotransduction-based regulation of flow. The blood vessel wall is a living tissue that quickly reacts to loads applied on it by the flowing blood. In any segment of a blood vessel, the endothelial and smooth muscle cells can sense unusual time variations in small-magnitude wall shear stress and large-amplitude wall stretch generated by abnormal hemodynamic stresses. These cells respond with a short-time scale (from seconds to hours) to adapt the vessel caliber. Since such adaptive cell activities can be described using mathematical models, a key objective of this volume is to identify the mesoscopic agents and nanoscopic mediators required to derive adequate mathematical models.  The resulting biomathematical models and corresponding simulation software can be incorporated into platforms developed in virtual physiology for improved understanding and training. Reviews structure and function of major constituents of the circulatory and respiratory apparatus Describes major cellular processes involved in signaling, interactions, and adaptive responses of physiological conduits Integrates biology, chemistry, and physics for the multidisciplinary exploration and modeling of physiological flows Focuses on mechanotransduction-induced regulation
650 0 _aPhysics.
650 0 _aCardiology.
650 0 _aBiological models.
650 0 _aHydraulic engineering.
650 0 _aBiomedical engineering.
650 1 4 _aPhysics.
650 2 4 _aBiophysics and Biological Physics.
650 2 4 _aBiomedical Engineering.
650 2 4 _aMathematical and Computational Biology.
650 2 4 _aSystems Biology.
650 2 4 _aEngineering Fluid Dynamics.
650 2 4 _aCardiology.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461459651
830 0 _aBiomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems,
_x2193-1682 ;
_v5
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-5966-8
912 _aZDB-2-PHA
999 _c95549
_d95549