000			03049nam a22004815i 4500
001			978-1-4614-5082-5
003			DE-He213
005			20140220082818.0
007			cr nn 008mamaa
008			121116s2013 xxu| s |||| 0|eng d
020			_a9781461450825 _9978-1-4614-5082-5
024	7		_a10.1007/978-1-4614-5082-5 _2doi
050		4	_aRB155-155.8
050		4	_aQH431
072		7	_aMFN _2bicssc
072		7	_aMED107000 _2bisacsh
082	0	4	_a611.01816 _223
082	0	4	_a599.935 _223
100	1		_aGaraulet, Marta. _eeditor.
245	1	0	_aChronobiology and Obesity _h[electronic resource] / _cedited by Marta Garaulet, Jose M. Ordovás.
264		1	_aNew York, NY : _bSpringer New York : _bImprint: Springer, _c2013.
300			_aXVI, 187 p. 35 illus., 34 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aPreface -- Foreword -- Discovery of the Clock mutant and the first mammalian clock gene and the links to obesity: Staring with animal #25 -- An introduction to chronobiology -- Adipose tissue as a peripheral clock -- Processes Underlying Chronodisruption and their Proposed Association with illness -- Obesity and Chronodisrruption:  An imbalance between energy intake and expenditure -- Sleep and MetS alterations -- Increased risk of diabetes due to obesity: does chronodisruption play a role? -- Genetics in chronobiology and obesity -- Chronobiology And Metabolic-Syndrome: From Genes To Systems Biology -- Index.
520			_aCircadian rhythms are such an innate part of our lives that we rarely pause to speculate why they even exist. Perhaps this is the reason why in the medical practice the circadian variability of hormones, metabolites, physiological behaviors or the relevance of time in the presence or absence of different pathologies, have been practically ignored in the past. Some studies have suggested that the disruption of the circadian system may be cause for obesity and manifestations of Metabolic Syndrome (MetS). Shift-work, sleep-deprivation and bright-light-exposure at night are related to increased adiposity (obesity) and prevalence of MetS. Chronobiology and Obesity examines recent advances that have led to researchers to find the relevant link which exists between chronobiology and obesity, but, as it is emphasized throughout the book, there is much more that needs to be explored between the connection.
650		0	_aMedicine.
650		0	_aHuman genetics.
650		0	_aEndocrinology.
650	1	4	_aBiomedicine.
650	2	4	_aHuman Genetics.
650	2	4	_aEndocrinology.
650	2	4	_aBiomedicine general.
700	1		_aOrdovás, Jose M. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781461450818
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-4614-5082-5
912			_aZDB-2-SBL
999			_c95308 _d95308