000 02783nam a22004575i 4500
001 978-1-4614-4660-6
003 DE-He213
005 20140220082816.0
007 cr nn 008mamaa
008 130109s2013 xxu| s |||| 0|eng d
020 _a9781461446606
_9978-1-4614-4660-6
024 7 _a10.1007/978-1-4614-4660-6
_2doi
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a614.5999
_223
100 1 _aLentzsch, Suzanne.
_eeditor.
245 1 0 _aGenetic and Molecular Epidemiology of Multiple Myeloma
_h[electronic resource] /
_cedited by Suzanne Lentzsch.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2013.
300 _aVII, 125 p. 15 illus., 13 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aPreface -- Genetics of Multiple Myeloma -- Gene expression signature in MGUS and multiple myeloma -- Cap-Dependent Protein Translation Initiation in Multiple Myeloma: an Attractive Target for Therapy -- IRES-dependent, CAP-independent translation in Multiple Myeloma -- Epigenetic gene silencing as a new target for multiple myeloma -- Role of Bone Disease in the Pathogenesis of Multiple Myeloma -- Index.
520 _aThis state-of-the-art book is written by a group of international experts to provide insight into the newest breakthroughs from basic pathogenesis to clinical aspects of multiple myeloma. The book provides a comprehensive overview of the genetic and molecular epidemiology of multiple myeloma in order to get a more refined and conclusive understanding of this disease.  Areas, which are covered include the characterization of different myeloma entities by genomics and proteomics, notch signaling and targeting protein translation as a new treatment for multiple myeloma, cell cycle control of plasma cell differentiation, the role of bone disease in the pathogenesis of multiple myeloma as well as the molecular interaction of multiple myeloma with a microenvironment. Genetic and Molecular Epidemiology of Multiple Myeloma is a valuable resource for cancer researchers, medical, surgical, and radiation oncologists.
650 0 _aMedicine.
650 0 _aOncology.
650 0 _aHuman genetics.
650 0 _aCytology.
650 1 4 _aBiomedicine.
650 2 4 _aCancer Research.
650 2 4 _aCell Biology.
650 2 4 _aHuman Genetics.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461446590
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-4660-6
912 _aZDB-2-SBL
999 _c95195
_d95195