000 03081nam a22005055i 4500
001 978-1-4614-4015-4
003 DE-He213
005 20140220082813.0
007 cr nn 008mamaa
008 120807s2013 xxu| s |||| 0|eng d
020 _a9781461440154
_9978-1-4614-4015-4
024 7 _a10.1007/978-1-4614-4015-4
_2doi
050 4 _aRB155-155.8
050 4 _aQH431
072 7 _aMFN
_2bicssc
072 7 _aMED107000
_2bisacsh
082 0 4 _a611.01816
_223
082 0 4 _a599.935
_223
100 1 _aSchedl, Tim.
_eeditor.
245 1 0 _aGerm Cell Development in C. elegans
_h[electronic resource] /
_cedited by Tim Schedl.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2013.
300 _aXI, 429 p. 50 illus., 43 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v757
505 0 _aIntroduction to germ cell development in C. elegans -- Germ cell specification -- Sex determination in the C. elegans germline -- Stem cell proliferation versus meiotic fate decision in C. elegans -- Physiological control of germline development -- Meiotic development in C. elegans -- Spermatogenesis -- Translational control in the C. elegans germ line -- Germ cell apoptosis and DNA damage responses -- Control of Oocyte Growth and Meiotic Maturation in C. elegans -- Fertilization -- The oocyte-to-embryo transition -- Epigenetic Control of Germline Development -- Using Caenorhabditis to explore the evolution of the germ line -- Index.
520 _aGerm cells in sexually reproducing metazoa, through the germline lineage, are the route by which genetic material and cytoplasmic constituents are passed from one generation to the next in the continuum of life.  Chapters in this book review germ cell development in the model organism Caenorhabditis elegans, discussing the biology, the genetics and the molecular mechanisms for various processes, as well as drawing comparisons with other organisms.  Processes discussed include specification of germ cell fate, meiosis, gametogenesis, environmental/ physiological controls, epigenetics and translational control, fertilization and the oocyte-to-embryo transition.  This book thus provides a comprehensive picture of the germline lineage and the continuum of life for the worm.
650 0 _aMedicine.
650 0 _aHuman genetics.
650 0 _aCytology.
650 0 _aDevelopmental biology.
650 1 4 _aBiomedicine.
650 2 4 _aHuman Genetics.
650 2 4 _aCell Biology.
650 2 4 _aDevelopmental Biology.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461440147
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v757
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-4015-4
912 _aZDB-2-SBL
999 _c95049
_d95049