000 04388nam a22004335i 4500
001 978-81-322-1533-2
003 DE-He213
005 20140220082526.0
007 cr nn 008mamaa
008 131025s2014 ii | s |||| 0|eng d
020 _a9788132215332
_9978-81-322-1533-2
024 7 _a10.1007/978-81-322-1533-2
_2doi
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a614.5999
_223
100 1 _aR. Sudhakaran, Perumana.
_eeditor.
245 1 0 _aPerspectives in Cancer Prevention-Translational Cancer Research
_h[electronic resource] /
_cedited by Perumana R. Sudhakaran.
264 1 _aNew Delhi :
_bSpringer India :
_bImprint: Springer,
_c2014.
300 _aXII, 168 p. 51 illus., 22 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _a1.Nutrition in Cancer: Evidence Based Nutrition Recommendations in Cancer Patients and Survivors -- 2.Tumor Stem Cell Enrichment by Anticancer Drugs: A Potential Mechanism of Tumor Recurrence -- 3. Curcumin: A potent candidate to be evaluated as a chemosensitizer in paclitaxel chemotherapy against cervical cancer -- 4. Azadirachta indica (Neem) and Neem Limonoids as Anticancer Agents: Molecular Mechanisms and Targets -- 5. In vitro studies on the antioxidant/antigenotoxic potential of aqueous fraction from Anthocephalus cadamba bark -- 6. Possible involvement of Signal Transducer and Activator of Transcription-3 (STAT3) Signaling Pathway in the Initiation and Progression of Hepatocellular Carcinoma -- 7. Simple Sequence Repeats In 5’ and 3’ flanking sequences of Cell Cycle Genes -- 8.Mechanisms of Chemopreventive Activity of Sulforaphane -- 9. Reciprocal relationship between VE-cadherin and Matrixmetalloproteinase expression in Endothelial cells and its Implications to Angiogenesis -- 10. Androgen receptor expression in human thyroid cancer tissues: a potential mechanism underlying the gender bias in the incidence of thyroid cancers -- 11.Novel co-ordination complexes of a few essential trace metals: Cytotoxic properties and lead identification for drug development for cancer -- 12.Why Gallbladder Cancer is common in Gangetic Belt? -- 13. Stress & Cancer Risk: The Possible Role of Work Stress.
520 _aBeing a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory or population studies into clinical application to reduce incidence of cancer , morbidity and mortality. It is becoming increasingly evident that cancer is a preventable disease. The IVth International Symposium on Translational Cancer Research held in Udaipur, India in December 2011, discussed various aspects of the biological processes in cancer cells and approaches to cancer prevention. A few contributions from this meeting are presented in this book, providing an in depth analysis of data on cancer prevention and therapeutics. These contributions are either critical reviews or research reports. The topics discussed include evidence-based nutritional recommendations for cancer patients and survivors, risk factors such as stress, enrichment of tumour stem cells by anticancer drug treatment contributing to tumour recurrence and the mechanism of anticancer effects of various natural products. Chemosensitizing effect of curcumin, anti-cancer effect of products from neem, action of sulforaphane and cytotoxic effect of a number of novel synthetic coordination complexes of trace metals have been discussed. Novel molecular targets of angiogenesis and molecular basis of the gender bias to thyroid cancer have also been discussed . This book provides useful information on translational cancer research to clinicians and biomedical scientists.
650 0 _aMedicine.
650 0 _aOncology.
650 1 4 _aBiomedicine.
650 2 4 _aCancer Research.
650 2 4 _aBiomedicine general.
650 2 4 _aOncology.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9788132215325
856 4 0 _uhttp://dx.doi.org/10.1007/978-81-322-1533-2
912 _aZDB-2-SBL
999 _c93740
_d93740