000			03811nam a22004935i 4500
001			978-3-642-40412-2
003			DE-He213
005			20140220082520.0
007			cr nn 008mamaa
008			131211s2014 gw | s |||| 0|eng d
020			_a9783642404122 _9978-3-642-40412-2
024	7		_a10.1007/978-3-642-40412-2 _2doi
050		4	_aR895-920
072		7	_aMMPH _2bicssc
072		7	_aMMP _2bicssc
072		7	_aMED008000 _2bisacsh
082	0	4	_a616.0757 _223
100	1		_aLuna, Antonio. _eeditor.
245	1	0	_aFunctional Imaging in Oncology _h[electronic resource] : _bBiophysical Basis and Technical Approaches - Volume 1 / _cedited by Antonio Luna, Joan C. Vilanova, L. Celso Hygino da Cruz Jr., Santiago E. Rossi.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg : _bImprint: Springer, _c2014.
300			_aXV, 549 p. 285 illus., 220 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aClinical and therapeutic approach to functional oncological imaging: Cancer biology: What’s important for imaging -- Imaging biomarkers in oncology as surrogate endpoints in clinical trials -- Role of functional-molecular imaging in oncology -- Radiotherapy and imaging -- New therapies and functional-molecular imaging -- Bioinformatics for cancer imaging. Imaging of cancer hallmarks: Imaging of angiogenesis -- Imaging of tumor metabolism: MR spectroscopy -- Imaging of tumor metabolism: 18-FDG PET -- Imaging of tumor metabolism: PET with other metabolites -- Imaging of hypoxia on PET -- Imaging of hypoxia on MRI. Functional imaging techniques in clinical use: Functional imaging in assessing and monitoring of treatment response -- Diffusion-weighted MR imaging -- Perfusion CT -- Perfusion MRI -- DCE-US: Evaluation of angiogenesis -- Spectroscopy in cancer -- Hybrid imaging: PET-CT and PET-MRI -- Dual and spectral energy CT: oncological applications -- US elastography: applications in tumors. Molecular imaging techniques in clinical use and in research: New molecular and functional imaging techniques -- Multiparametric imaging.
520			_aIn the new era of functional and molecular imaging, both currently available imaging biomarkers and biomarkers under development are expected to lead to major changes in the management of oncological patients. This well-illustrated two-volume book is a practical manual on the various imaging techniques capable of delivering functional information on cancer, including preclinical and clinical imaging techniques, based on US, CT, MRI, PET and hybrid modalities. This first volume explains the biophysical basis for these functional imaging techniques and describes the techniques themselves. Detailed information is provided on the imaging of cancer hallmarks, including angiogenesis, tumor metabolism, and hypoxia. The techniques and their roles are then discussed individually, covering the full range of modalities in clinical use as well as new molecular and functional techniques. The value of a multiparametric approach is also carefully considered.
650		0	_aMedicine.
650		0	_aRadiology, Medical.
650		0	_aOncology.
650	1	4	_aMedicine & Public Health.
650	2	4	_aImaging / Radiology.
650	2	4	_aOncology.
650	2	4	_aDiagnostic Radiology.
700	1		_aVilanova, Joan C. _eeditor.
700	1		_aHygino da Cruz Jr., L. Celso. _eeditor.
700	1		_aRossi, Santiago E. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783642404115
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-642-40412-2
912			_aZDB-2-SME
999			_c93421 _d93421