000 04128nam a22004695i 4500
001 978-3-642-39495-9
003 DE-He213
005 20140220082519.0
007 cr nn 008mamaa
008 131129s2014 gw | s |||| 0|eng d
020 _a9783642394959
_9978-3-642-39495-9
024 7 _a10.1007/978-3-642-39495-9
_2doi
050 4 _aRC109-216
072 7 _aMJCJ
_2bicssc
072 7 _aMED022090
_2bisacsh
082 0 4 _a616.9
_223
100 1 _aMassoud, Ahmad.
_eeditor.
245 1 0 _aImmunology of Aging
_h[electronic resource] /
_cedited by Ahmad Massoud, Nima Rezaei.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2014.
300 _aXIX, 406 p. 31 illus., 29 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aAn Introduction on the old age and aging of the immune system -- The immune system, a marker and modulator of the rate of aging -- Age-associated alterations of pleiotropic stem cell and the therapeutic implication of stem cell therapy in aging -- A role for epigenetic modulation of the innate immune response during aging -- Basophil, eosinophil and neutrophil functions in the elderly -- Dendritic cells and dysregulated immunity in the elderly -- Natural killer cell immunosenescence and cancer in the elderly -- Pattern recognition receptors and aging -- Impact of ageing on T cell repertoire and immunity -- T cell mediated immunity in the immunosenescence process -- Biological and phenotypic alterations of T cells in aging -- T cells seen from the metabolic and aging perspective -- Age-related alterations in regulatory T cells -- Effects of aging on B cells -- The role of MicroRNAs in immunosenescence process -- Immunogenetics of Aging -- Aging immunity and infection -- Influenza infection in the elderly -- Optimising response to vaccination in the elderly -- Nutrition, immunity and aging -- Diet and immunosenescence -- Dietary Intake and impact of zinc supplementation on the immune functions in elderly: nutrigenomic approach -- Physiological and pathological role of reactive oxygen species in the immune cells -- Oxidative stress in aging -- Skin aging and the immune system -- Aging immunity and the impact of physical exercise.
520 _aThe rapidity of scientific progress over the last few years guarantees the utility of a new collection of state-of-the-art reviews on the immunology of ageing. The aim of this authoritative book is to summarize current knowledge on the cellular and molecular aspects of the ageing immune system and their clinical relevance. The book is a result of extensive collaboration of more than sixty of the greatest thinkers and scholars in the field, in cooperation with a number of junior colleagues.   Immunology of Aging presents the most up-to-date information on the scientific issues addressed by research into ageing of the immune system, providing insights into the effects of this process on susceptibilities to those diseases which are most common among elders. The retrieval strategies used to slow down the decline in the immune system in the elderly are another subject detailed extensively.   By providing a broad overview of immunosenescence and its consequences, as well as their potential modulation, this book will fill a gap in a timely manner. It will be of value to all immunologists, whether novice or experienced, as well as geriatricians and epidemiologists.
650 0 _aMedicine.
650 0 _aImmunology.
650 0 _aGeriatrics.
650 0 _aEmerging infectious diseases.
650 1 4 _aMedicine & Public Health.
650 2 4 _aInfectious Diseases.
650 2 4 _aGeriatrics/Gerontology.
650 2 4 _aImmunology.
700 1 _aRezaei, Nima.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642394942
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-39495-9
912 _aZDB-2-SME
999 _c93326
_d93326