000 03566nam a22005535i 4500
001 978-3-642-39432-4
003 DE-He213
005 20140220082519.0
007 cr nn 008mamaa
008 131129s2014 gw | s |||| 0|eng d
020 _a9783642394324
_9978-3-642-39432-4
024 7 _a10.1007/978-3-642-39432-4
_2doi
050 4 _aQR46
072 7 _aMMFM
_2bicssc
072 7 _aMED052000
_2bisacsh
082 0 4 _a616.9041
_223
100 1 _aKurzai, Oliver.
_eeditor.
245 1 0 _aHuman Fungal Pathogens
_h[electronic resource] /
_cedited by Oliver Kurzai.
250 _a2nd ed. 2014.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2014.
300 _aXXII, 298 p. 59 illus., 33 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aThe Mycota, A Comprehensive Treatise on Fungi as Experimental Systems for Basic and Applied Research ;
_v12
505 0 _aFrom Commensal to Pathogen: Candida albicans -- Aspergillus fumigatus: Saprotroph to Pathogen -- Systems Biology Approaches to Understand and Predict Fungal Virulence -- Receptor-Ligand Interactions in Fungal Infections -- Macrophages in the Immune Response against Cryptococcus -- T Cell Responses in Fungal Infections -- Molecular Mechanisms of Histoplasma Pathogenesis -- Visualizing Immune Responses in Fungal Infections – Established and Novel Methods -- Mucosal Immunology in Candida albicans Infection -- Invasive Aspergillosis in the Intensive Care Unit -- Molecular Epidemiology of Pneumocystis Outbreaks -- Infections Caused by Mucorales -- Diagnostics of Fungal Infections -- Therapeutic Strategies in Fungal Infections -- Antifungal Pharmacokinetics.
520 _aWhereas plant and insect infections are commonly caused by fungi, only a small minority of the vast diversity of fungal species is pathogenic to humans. Despite this, fungal infections cause considerable morbidity and mortality worldwide. This volume is dedicated to the biology, clinical presentation and management of invasive fungal infections. Major pathogenic fungi are introduced by world-leading experts and the basic principles of fungal virulence are reviewed in the light of new results and experimental technologies that offer unprecedented insights into invasive infections caused by Aspergillus, Candida, Cryptococcus, Pneumocystis and Mucorales. In parallel, the clinical presentation of invasive fungal infections and current approaches to their diagnosis and treatment are summarized to provide an overview of human pathogenic fungi, linking pathogen biology to the clinical presentation of disease.
650 0 _aMedicine.
650 0 _aImmunology.
650 0 _aMicrobiology.
650 0 _aAllergy.
650 0 _aCytology.
650 0 _aMicrobial genetics.
650 1 4 _aBiomedicine.
650 2 4 _aMedical Microbiology.
650 2 4 _aImmunology.
650 2 4 _aAllergology.
650 2 4 _aCell Biology.
650 2 4 _aEukaryotic Microbiology.
650 2 4 _aMicrobial Genetics and Genomics.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642394317
830 0 _aThe Mycota, A Comprehensive Treatise on Fungi as Experimental Systems for Basic and Applied Research ;
_v12
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-39432-4
912 _aZDB-2-SBL
999 _c93320
_d93320