000 03674nam a22005175i 4500
001 978-3-540-72314-1
003 DE-He213
005 20140220082515.0
007 cr nn 008mamaa
008 131004s2014 gw | s |||| 0|eng d
020 _a9783540723141
_9978-3-540-72314-1
024 7 _a10.1007/978-3-540-72314-1
_2doi
050 4 _aRM845-862.5
072 7 _aMJCL1
_2bicssc
072 7 _aMED080000
_2bisacsh
082 0 4 _a615.842
_223
100 1 _aRubin, Philip.
_eeditor.
245 1 0 _aALERT - Adverse Late Effects of Cancer Treatment
_h[electronic resource] :
_bVolume 1: General Concepts and Specific Precepts /
_cedited by Philip Rubin, Louis S. Constine, Lawrence B. Marks.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2014.
300 _aXXIV, 311 p. 93 illus., 43 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMedical Radiology,
_x0942-5373
505 0 _aBioContinuum of Effects of Multimodal Therapy -- BioMolecular Mechanisms and Pathways of Normal Tissue Damage -- BioPathology of Radiation and Chemotherapy -- BioImaging of the Longitudinal Normal Tissue Injury -- BioScoring Systems for Acute and Late Effects -- BioPediatric Complexities of Growth and Development -- Bioepidemiology -- BioGenetic and Host Implications -- Radiotherapy-Induced Biocarcinogenesis and Leukemogenesis -- BioManagement and BioPrevention.-BioSurveillance and Longitudinal Lifelong Guidelines -- Specific Precept: Medical Legal Issues: Malpractice Issues -- Insurance, Economics: Cost of Care -- Nursing -- Psychologic Issues -- Social Worker Issues: Quality of Life and Activities of Daily Living.
520 _aThe literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT – Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system differently and is expressed continually over time. Essentially, radiation and chemotherapy are intense biologic modifiers that allow for cancer cure and cancer survivorship but accelerate senescence of normal tissues and increase the incidence of age-related diseases and second malignant tumors. Volume 1 of this two-volume work focuses on the general concepts and principles relevant to late effects and on the dynamic interplay of molecular, cytologic and histopathologic events that lead to altered physiologic and metabolic functions and their clinical manifestations. Chapters are also included on legal issues, economic aspects, nursing, psychological issues and quality of life.
650 0 _aMedicine.
650 0 _aRadiology, Medical.
650 0 _aRadiotherapy.
650 0 _aOncology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aRadiotherapy.
650 2 4 _aImaging / Radiology.
650 2 4 _aOncology.
650 2 4 _aDiagnostic Radiology.
700 1 _aConstine, Louis S.
_eeditor.
700 1 _aMarks, Lawrence B.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783540723134
830 0 _aMedical Radiology,
_x0942-5373
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-540-72314-1
912 _aZDB-2-SME
999 _c93100
_d93100