000 03956nam a22005175i 4500
001 978-3-319-01472-2
003 DE-He213
005 20140220082508.0
007 cr nn 008mamaa
008 131004s2014 gw | s |||| 0|eng d
020 _a9783319014722
_9978-3-319-01472-2
024 7 _a10.1007/978-3-319-01472-2
_2doi
050 4 _aRG499.2-991
050 4 _aRG600-650
072 7 _aMJT
_2bicssc
072 7 _aMED033000
_2bisacsh
082 0 4 _a618.2
_223
100 1 _aKällén, Bengt.
_eauthor.
245 1 0 _aEpidemiology of Human Congenital Malformations
_h[electronic resource] /
_cby Bengt Källén.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2014.
300 _aIX, 170 p. 32 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aA Short History of Birth Defect Epidemiology -- Genetic and Non-genetic Factors in the Origin of Congenital Malformations -- Ascertainment of Children with Congenital Malformations -- Statistical Considerations -- Epidemiological Methods -- Neural Tube Defects -- Microcephaly -- Hydrocephaly -- Agenesis of Corpus Callosum and Holoprosencephaly -- Severe Eye Malformations -- Severe Ear Malformations -- Cardiovascular Defects -- Orofacial Clefts -- Atresia or Stenosis of the Alimentary Tract -- Pyloric Stenosis -- Malrotation of the Gut -- Megacolon -- Hypospadias -- Epispadias, Cloacal and Bladder Exstrophy -- Severe Renal Malformations -- Posterior Urethral Valve -- Pes Equinovarus -- Other Foot Deformities than Pes Equinovarus -- Polydactyly and Syndactyly -- Limb Reduction Defects -- Craniostenosis -- Diaphragmatic Hernia -- Abdominal Wall Defects -- Children with multiple malformations -- ”Syndromes” -- Down Syndrome -- Explanation and Prevention of Birth Defects -- Eight Commandments: Rules for the Interpretation of Birth Defect Epidemiological Studies.
520 _aThe subject of this book is to describe the occurrence of congenital malformations among children born and what risk factors exist. Population data are presented for a number of malformations, ascertained with the use of data from the Swedish national health registers for the period 1998-2010 corresponding to some 1.3 million births, together with prospectively collected information on a group of exposures of possible interest. The structure of the analysis is such that it excludes studies of, for instance, nutrition, alcohol or street drug use and many other lifestyle factors where prospective information or independent register information is difficult or impossible to obtain. Epidemiology of Human Congenital Malformations culminates with a discussion on how the presence of malformations can be explained and various possibilities for the prevention of birth defects. Moreover, it will include a series of instructions on how to read epidemiological literature in this field making it an essential resource both for those currently working in the field of reproductive epidemiology or those intending to enter it. It will additionally be useful for doctors working with malformations, either as obstetricians, neonatologists or pediatricians.
650 0 _aMedicine.
650 0 _aObstetrics.
650 0 _aMaternal and infant welfare.
650 0 _aPediatrics.
650 0 _aReproductive Medicine.
650 0 _aEpidemiology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aObstetrics/Perinatology.
650 2 4 _aMaternal and Child Health.
650 2 4 _aReproductive Medicine.
650 2 4 _aEpidemiology.
650 2 4 _aPediatrics.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319014715
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-319-01472-2
912 _aZDB-2-SME
999 _c92667
_d92667