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001 978-1-4614-8833-0
003 DE-He213
005 20140220082503.0
007 cr nn 008mamaa
008 131019s2014 xxu| s |||| 0|eng d
020 _a9781461488330
_9978-1-4614-8833-0
024 7 _a10.1007/978-1-4614-8833-0
_2doi
050 4 _aRC705-779
072 7 _aMJL
_2bicssc
072 7 _aMED079000
_2bisacsh
082 0 4 _a616.2
_223
100 1 _aGuidot, David M.
_eeditor.
245 1 0 _aAlcohol Use Disorders and the Lung
_h[electronic resource] :
_bA Clinical and Pathophysiological Approach /
_cedited by David M. Guidot, Ashish J. Mehta.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Humana Press,
_c2014.
300 _aX, 252 p. 26 illus., 15 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aRespiratory Medicine,
_x2197-7372 ;
_v14
505 0 _aA Brief History of Alcohol Use and Abuse in Human History -- Overview of the Evolving Recognition of the Health Effects of Excessive Alcohol Use Over the Past Two Centuries Including the Classic Citations -- Current Definitions of Alcohol Use Disorders and the Use of Validated Questionnaires in Clinical Practice and Research -- The Epidemiology of Alcohol Abuse and Pneumonia -- The Epidemiology of Alcohol and Acute Respiratory Distress Syndrome -- Alcohol, the Upper Airway, and Mucociliary Dysfunction in the Conducting Airways -- Alcohol and the Alveolar Macrophage -- Alcohol and the Alveolar Epithelium -- Alcohol-Mediated Oxidative Stress in the Airway: The Unique Role of Thiol Depletion -- Alcohol and the Adaptive Immune Response in the Airway: Dendritic Cell and Lymphocyte Impairments -- Alcohol Impairment of Granulocyte Function During Lung Infection -- Disruption in the Dynamic Balance Between Transforming Growth Factor-β and Granulocyte/Macrophage Colony-stimulating Factor Signaling within the Alveolar Space of the Alcoholic Lung: Impact on Epithelial and Macrophage Function -- Alcohol-mediated Zinc Deficiency within the Alveolar Space: A Potential Fundamental Mechanism Underlying Oxidative Stress and Cellular Dysfunction in the Alcoholic Lung -- The Impact of Alcohol Abuse on Multiple Organ Dysfunction in the Surgical Patient -- Alcohol and HIV: Experimental and Clinical Evidence of Combined Impact on the Lung -- Maternal Alcohol Use and the Neonate.
520 _aAlcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach is an excellent resource for clinicians who care for individuals affected by alcohol use disorders in diverse settings. Although alcohol abuse alone does not cause acute lung injury, it renders the lung susceptible to dysfunction in response to the inflammatory stresses of sepsis, trauma, and other clinical conditions recognized to cause acute lung injury. In parallel, these same pathophysiological effects of alcohol abuse significantly increase the risk of a wide range of serious lung infections. Many clinicians involved in the primary treatment of alcohol use disorders, such as addiction psychiatrists, will find this text of interest as it will expand their understanding of the health consequences of alcohol use disorders. In parallel, clinicians who specialize in pulmonary and/or critical care medicine will have a unique resource that provides a comprehensive review of the pathophysiology of alcohol-related lung disorders and insights into evolving therapeutic options in these vulnerable individuals. Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach fills a gap in the literature and presents the evolving clinical research that may soon lead to novel therapies that can improve lung health in individuals with alcohol use disorders and co-existing conditions such as HIV infection.
650 0 _aMedicine.
650 0 _aCritical care medicine.
650 0 _aInternal medicine.
650 0 _aPneumology.
650 0 _aPsychiatry.
650 1 4 _aMedicine & Public Health.
650 2 4 _aPneumology/Respiratory System.
650 2 4 _aIntensive / Critical Care Medicine.
650 2 4 _aPsychiatry.
650 2 4 _aInternal Medicine.
700 1 _aMehta, Ashish J.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461488323
830 0 _aRespiratory Medicine,
_x2197-7372 ;
_v14
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-8833-0
912 _aZDB-2-SME
999 _c92258
_d92258