000 02493nam a22004815i 4500
001 978-1-4614-8809-5
003 DE-He213
005 20140220082503.0
007 cr nn 008mamaa
008 131024s2014 xxu| s |||| 0|eng d
020 _a9781461488095
_9978-1-4614-8809-5
024 7 _a10.1007/978-1-4614-8809-5
_2doi
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a614.5999
_223
100 1 _aRosenblatt, Joseph D.
_eeditor.
245 1 0 _aAdvances in Tumor Immunology and Immunotherapy
_h[electronic resource] /
_cedited by Joseph D. Rosenblatt, Eckhard R. Podack, Glen N. Barber, Augusto Ochoa.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2014.
300 _aIX, 371 p. 35 illus., 29 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aCurrent Cancer Research
520 _aThis volume explores recent advances in understanding of fundamental immunology  and insights into  the dynamic interactions between tumors and the immune system, that  provide new opportunities  for therapeutic  intervention in cancer.  Chapter topics include evolving paradigms in the innate and adaptive response,   newly appreciated immunosuppressive mechanisms,  and  novel preclinical  strategies for manipulation of the immune system for therapeutic benefit in cancer. In addition, recent successes in the clinic, and emerging opportunities are covered. Future possibilities, such as the use of antibody engineering, fusion proteins,  and the retargeting of immune cells through T-cell receptor engineering are discussed by  leaders in the field,  focusing  on recent clinical experience, promising technologies, and challenges to clinical success.
650 0 _aMedicine.
650 0 _aOncology.
650 0 _aToxicology.
650 1 4 _aBiomedicine.
650 2 4 _aCancer Research.
650 2 4 _aPharmacology/Toxicology.
700 1 _aPodack, Eckhard R.
_eeditor.
700 1 _aBarber, Glen N.
_eeditor.
700 1 _aOchoa, Augusto.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461488088
830 0 _aCurrent Cancer Research
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-8809-5
912 _aZDB-2-SME
999 _c92252
_d92252