000 02778nam a22005175i 4500
001 978-1-4614-7783-9
003 DE-He213
005 20140220082459.0
007 cr nn 008mamaa
008 130816s2014 xxu| s |||| 0|eng d
020 _a9781461477839
_9978-1-4614-7783-9
024 7 _a10.1007/978-1-4614-7783-9
_2doi
050 4 _aRB155-155.8
050 4 _aQH431
072 7 _aMFN
_2bicssc
072 7 _aMED107000
_2bisacsh
082 0 4 _a611.01816
_223
082 0 4 _a599.935
_223
100 1 _aBaldi, Elisabetta.
_eeditor.
245 1 0 _aGenetic Damage in Human Spermatozoa
_h[electronic resource] /
_cedited by Elisabetta Baldi, Monica Muratori.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2014.
300 _aXIII, 195 p. 22 illus., 17 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v791
505 0 _aStructure of chromatin in spermatozoa -- Genomic changes in spermatozoa of aging male -- Chromosomal aberrations and aneuploidies -- The sperm epigenome: implications for the embryo -- Paternal reprogramming of genome: transgenerational effects -- Alterations in protamination -- Sperm DNA fragmentation and base oxidation -- Iatrogenic Genetic damage -- Sperm selection: effect on sperm DNA quality -- Effect of antioxidant treatments on sperm genetic damage -- Index.
520 _aThere are several types of damage that can be found in the male gamete. Genetic damage in spermatozoa can originate during spermatogenesis, or it can originate during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. This book provides a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.
650 0 _aMedicine.
650 0 _aHuman genetics.
650 0 _aEndocrinology.
650 0 _aReproductive Medicine.
650 1 4 _aBiomedicine.
650 2 4 _aHuman Genetics.
650 2 4 _aEndocrinology.
650 2 4 _aReproductive Medicine.
700 1 _aMuratori, Monica.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461477822
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v791
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-7783-9
912 _aZDB-2-SBL
999 _c92055
_d92055