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001 9781351201438
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008 200304s2020 xx o 000 0 eng d
040 _aOCoLC-P
_beng
_erda
_epn
_cOCoLC-P
020 _a9781351201438
_q(electronic bk.)
020 _a1351201433
_q(electronic bk.)
020 _a9781351201421
_q(electronic bk. : PDF)
020 _a1351201425
_q(electronic bk. : PDF)
020 _z9781138563889
020 _a9781351201414
_q(electronic bk. : EPUB)
020 _a1351201417
_q(electronic bk. : EPUB)
020 _a9781351201407
_q(electronic bk. : Mobipocket)
020 _a1351201409
_q(electronic bk. : Mobipocket)
024 3 _a9781351201438
035 _a(OCoLC)1142969249
035 _a(OCoLC-P)1142969249
050 4 _aQD415
_b.H57 2020eb
082 0 4 _a572
_223
100 1 _aHirata, Fumio,
_eauthor.
245 1 0 _aExploring life phenomena with statistical mechanics of molecular liquids /
_cFunio Hirata.
264 1 _a[Place of publication not identified] :
_bCRC Press,
_c[2020].
300 _a1 online resource (x, 288 pages)
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
505 0 _aGeneral Introduction. Fundamentals: Basic Concepts Related to Statistical Mechanics. Statistical Mechanics of Liquid and Solutions. Dynamics of Liquids and Solutions. Theory of Biomolecular Solvation and Molecular Recognition. Structural Fluctuation and Dynamics of Protein in Aqueous Solutions. Applications of the Theories to In-silico Drug Discovery. References. Epilogue.
520 _aIn a living body, a variety of molecules are working in a concerted manner to maintain its life, and to carry forward the genetic information from generation to generation. A key word to understand such processes is "water," which plays an essential role in life phenomena. This book sheds light on life phenomena, which are woven by biomolecules as warp and water as weft, by means of statistical mechanics of molecular liquids, the RISM and 3D-RISM theories, both in equilibrium and non-equilibrium. A considerable number of pages are devoted to basics of mathematics and physics, so that students who have not majored in physics may be able to study the book by themselves. The book will also be helpful to those scientists seeking better tools for the computer-aided-drug-discovery. Explains basics of the statistical mechanics of molecular liquids, or RISM and 3D-RISM theories, and its application to water. Provides outline of the generalized Langevin theory and the linear response theory, and its application to dynamics of water. Applies the theories to functions of biomolecular systems. Applies the theories to the computer aided drug design. Provides a perspective for future development of the method.
588 _aOCLC-licensed vendor bibliographic record.
650 0 _aBiomolecules.
650 0 _aStatistical mechanics.
650 0 _aBiomolecules
_xMathematics.
650 0 _aProtein-protein interactions.
856 4 0 _3Taylor & Francis
_uhttps://www.taylorfrancis.com/books/9781351201438
856 4 2 _3OCLC metadata license agreement
_uhttp://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf
999 _c130139
_d130139