000			04036cam a2200517Ii 4500
001			9781315374727
003			FlBoTFG
005			20220509193044.0
006			m o d
007			cr |n|||||||||
008			210121s2021 flu ob 001 0 eng d
040			_aOCoLC-P _beng _erda _cOCoLC-P
020			_a1315357089 _qelectronic book
020			_a9781315357089 _q(electronic bk.)
020			_a9781315374727 _q(electronic bk.)
020			_a1315374722 _q(electronic bk.)
020			_a9781439853276 _q(electronic bk. : PDF)
020			_a1439853274 _q(electronic bk. : PDF)
020			_a9781315338026 _q(electronic bk. : Mobipocket)
020			_a1315338025 _q(electronic bk. : Mobipocket)
020			_z1138323586
020			_z9781138323582
035			_a(OCoLC)1232204950
035			_a(OCoLC-P)1232204950
050		4	_aRS431.A64 _bT48 2021
072		7	_aMED _x058160 _2bisacsh
072		7	_aMED _x062000 _2bisacsh
072		7	_aMED _x071000 _2bisacsh
072		7	_aMMG _2bicssc
082	0	4	_a615.7/98 _223
100	1		_aThurston, David E., _eauthor.
245	1	0	_aChemistry and pharmacology of anticancer drugs / _cDavid E. Thurston, Ilona Pysz.
264		1	_aBoca Raton : _bCRC Press, _c2021.
300			_a1 online resource
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
520			_aWhile drug therapies developed in the last 80 years have markedly improved treatment outcomes and the management of some types of cancers, the lack of effectiveness and side effects associated with the most common treatment types remain unacceptable. However, recent technological advances are leading to improved therapies based on targeting distinct biological pathways in cancer cells. Chemistry and Pharmacology of Anticancer Drugs is a comprehensive survey of all families of anticancer agents and therapeutic approaches currently in use or in advanced stages of clinical trials, including biological-based therapies. The book is unique in providing molecular structures for all anticancer agents, discussing them in terms of history of development, chemistry, mechanism of action, structure-function relationships, and pharmacology. It also provides relevant information on side effects, dosing, and formulation. The authors, renowned scientists in cancer research and drug discovery, also provide up-to-date information on the drug discovery process, including discussions of new research tools, tumor-targeting strategies, and fundamental concepts in the relatively new areas of precision medicine and chemoprevention. Chemistry and Pharmacology of Anticancer Drugs is an indispensable resource for cancer researchers, medicinal chemists and other biomedical scientists involved in the development of new anticancer therapies. Its breadth of coverage, clear explanations, and illustrations also make it suitable for undergraduate and postgraduate courses in medicine, pharmacy, nursing, dentistry, nutrition, the biomedical sciences, and related disciplines. Key Features: Summarizes the fundamental causes of cancer, modes of treatment, and strategies for cancer drug discovery Brings together a broad spectrum of information relating to the chemistry and pharmacology of all families of anticancer agents and therapies Includes up-to-date information on cutting-edge aspects of cancer treatments such as biomarkers, pharmacogenetics, and pharmacogenomics Features new chapters on the "Evolution of Anticancer Therapies", "Antibody-Based Therapies", and "Cancer Chemoprevention"
588			_aOCLC-licensed vendor bibliographic record.
650		0	_aAntineoplastic agents.
650		7	_aMEDICAL / Nursing / Oncology & Cancer _2bisacsh
650		7	_aMEDICAL / Oncology _2bisacsh
650		7	_aMEDICAL / Pharmacology _2bisacsh
700	1		_aPysz, Ilona, _eauthor.
856	4	0	_3Taylor & Francis _uhttps://www.taylorfrancis.com/books/9781315374727
856	4	2	_3OCLC metadata license agreement _uhttp://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf
999			_c128985 _d128985