000			04409cam a2200361Ii 4500
001			9781315206547
008			180331t20172017si ad ob 001 0 eng d
020			_a9781315206547 _q(e-book : PDF)
020			_a9781351797337 _q(e-book: Mobi)
020			_a9781351797351 _q(e-book: PDF)
020			_a9789814669986 _q(e-book)
020			_z9789814669979 _q(hardback)
024	7		_a10.1201/9781315206547 _2doi
035			_a(OCoLC)990156516
040			_aFlBoTFG _cFlBoTFG _erda
050		4	_aQP519.9.I42 _bI49 2017
082	0	4	_a616.0756 _bI336
245	0	0	_aImmunoassays : _bdevelopment, applications and future trends / _cedited by Richard O'Kennedy, Caroline Murphy.
264		1	_aSingapore : _bPan Stanford Publishing, _c[2017]
264		4	_c©2017
300			_a1 online resource (xxxi, 437 pages)
336			_atext _2rdacontent
337			_acomputer _2rdamedia
338			_aonline resource _2rdacarrier
505	0	0	_tchapter 1 An Overview of Immunoassays / _r Caroline Murphy Sarah Gilgunn Richard O’Kennedy -- _tchapter 2 Recombinant Antibodies for Diagnostic Applications: Design Considerations and Structural Correlates / _r Stephen Hearty Richard O’Kennedy -- _tchapter 3 Surfaces and Immobilisation Strategies for Use in Immunoassay Development / _r Chandra K. Dixit Paul Conroy -- _tchapter 4 Immunoassay Validation / _r Paul Leonard -- _tchapter 5 Lab-on-a-Chip Immunoassay Systems / _r Barry Byrne Louise M. Barrett -- _tchapter 6 Clinical Applications of Immunoassays / _r Karen Lawler Gregor Kijanka -- _tchapter 7 Immunoassay-Based Detection of Infectious and Parasitic Diseases / _r Paul J. Conroy -- _tchapter 8 Detection of Food, Agricultural and Aquatic Contaminants / _r Marie Le Berre Caroline Viguier Caroline Murphy Niamh Gilmartinb -- _tchapter 9 Next-Generation Immunoassays / _r Valerie Fitzgerald Paul Leonard -- _tchapter 10 Recent Trends and the Future of Electrochemical Immunoassay Systems / _r Frank Davis Seamus Higson -- _tchapter 11 Optical Signal Transduction with an Emphasis on the Application of Surface Plasmon Resonance (SPR) in Antibody Characterisation / _r Caroline Murphy Aoife Crawley Hannah Byrne Kara Moran Jenny Fitzgerald Richard O’Kennedy -- _tchapter 12 Protocols for Key Steps in the Development of an Immunoassay / _r Caroline Murphy Richard O’Kennedy.
520			_aThe concept behind this book is to provide a detailed and practical overview of the development and use of immunoassays in many different areas. Immunoassays are analytical tests that utilise antibodies to measure the amount, activity or identity of an analyte. This book is designed to provide a critical and helpful insight into the subject and to give the user practical information that may be of assistance in assay format selection, antibody generation/selection and choice of appropriate detection strategies. It is comprised of 13 chapters written by highly experienced researchers in the fields of antibody-based research, immunoassay development, assay validation, diagnostics and microfluidics. Beginning with a comprehensive survey of antibodies, immunoassay formats and signalling systems, the book elucidates key topics related to the development of an ideal antibody-based sensor, focuses on the important topic of surface modification, explores key parameters in the immobilisation of antibodies onto solid surfaces, discusses the move to 'lab-on-a-chip'-based devices and investigates the key parameters necessary for their development. Three of the chapters are dedicated to the areas of clinical diagnostics, infectious disease monitoring and food security, where immunoassay-based applications have become highly valuable tools. The future of immunoassays, including next-generation immunoassays, electrochemical-immunoassays and 'lab-on-a-chip'-based systems, is also discussed. The book also covers the use of optical detection systems (with a focus on surface plasmon resonance) in immunoassays, provides a compilation of important, routinely used immunoassay protocols and addresses problems that may be encountered during assay development.--Provided by publisher.
650		0	_aImmunoassay _xResearch.
650		0	_aImmunoassay.
650		0	_aImmunodiagnosis.
700	1		_aMurphy, Caroline, _eeditor.
700	1		_aO'Kennedy, Richard, _eeditor.
776	0	8	_iPrint version: _z9789814669979
856	4	0	_uhttps://www.taylorfrancis.com/books/9781315206547 _zClick here to view.
999			_c127933 _d127933