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| 001 | 9781498717410 | ||
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| 008 | 170915s2019 flua ob 001 0 eng d | ||
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_a9781315119847 _q(e-book) |
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| 024 | 7 |
_a10.1201/9781315119847 _2doi |
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| 035 |
_a(OCoLC)994508887 _z(OCoLC)1050336982 _z(OCoLC)1050694819 _z(OCoLC)1053981568 _z(OCoLC)1056767161 _z(OCoLC)1057769041 _z(OCoLC)1067246876 _z(OCoLC)1082976254 |
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| 035 | _a(OCoLC-P)994508887 | ||
| 050 | 4 |
_aQR182.2.M36 _bS97 2018eb |
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_aHEA _x039000 _2bisacsh |
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_aPHVN _2bicssc |
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| 082 | 0 | 4 | _a616.07/9 |
| 245 | 0 | 0 |
_aSystems immunology : _ban introduction to modeling methods for scientists / _cedited by Jayajit Das, Ciriyam Jayaprakash. |
| 264 | 1 |
_aBoca Raton, FL : _bCRC Press, _c[2019] |
|
| 264 | 4 | _c©2019 | |
| 300 |
_a1 online resource (xx, 334 pages) : _billustrations. |
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| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 490 | 1 | _aFoundations of biochemistry and biophysics | |
| 505 | 0 | _aIntroduction to basic concepts in immunology / Roxana Khazen and Salvatore Valitutti -- Overview of mechanistic modeling: techniques, approximations, and assumptions / Steven M. Abel -- The fundamentals of statistical data analysis / William C.L. Stewart -- Using data to guide model construction: application of principal component analysis and related methods in immunology research / Kathryn Miller-Jensen -- An introduction to rule-based modeling of immune receptor signaling / John A.P. Sekar, James R. Faeder -- Boolean models in immunology / Reinhard Laubenbacher and Elena Dimitrova -- From evolutionary computation to phenotypic spandrels: inverse problem for immune ligand recognition / Paul François and Mathieu Hemery -- Zen and the art of parameter estimation in systems biology / Christopher R. Myers -- Spatial kinetics in immunological modeling / Daniel Coombs and Byron Goldstein -- Analysis and modeling of single cell data / Derya Altintan, Jascha Diemer, and Heinz Koeppl -- Quantifying lymphocyte receptor diversity / Thierry Mora and Aleksandra M. Walczak -- Antigen receptor diversification during immune responses / Miri Michaeli and Ramit Mehr -- Quantitative modeling of mast cell signaling / Lily A. Chylek, David A. Holowka, Barbara A. Baird, and William S. Hlavacek -- Physical models in immune signaling / Jayajit Das -- Population dynamics of host and pathogens / Amber M. Smith, Ruy M. Ribeiro, and Alan S. Perelson -- Viral fitness landscapes: a physical sciences perspective / Gregory R. Hart and Andrew L. Ferguson -- A wish-list for modeling immunological synapses / Michael L. Dustin. | |
| 520 | 2 | _a"New experimental techniques in immunology have produced large and complex data sets that require quantitative modeling for analysis. This book provides a complete overview of computational immunology, from basic concepts to mathematical modeling at the single molecule, cellular, organism, and population levels. It showcases modern mechanistic models and their use in making predictions, designing experiments, and elucidating underlying biochemical processes. The book begins with an introduction to data analysis, approximations, and assumptions used in model building. Core chapters address models and methods for studying immune responses, with fundamental concepts clearly introduced and defined for the non-specialist."--Provided by publisher. | |
| 588 | _aOCLC-licensed vendor bibliographic record. | ||
| 650 | 0 |
_aImmunology _xMathematical models. |
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| 650 | 0 | _aImmunoinformatics. | |
| 650 | 0 | _aSystems biology. | |
| 650 | 0 | 7 |
_aMEDICAL _xImmunology. _2bisacsh |
| 650 | 0 | 7 |
_aSCIENCE _xPhysics. _2bisacsh |
| 650 | 7 |
_aMATHEMATICS / Applied _2bisacsh |
|
| 650 | 7 |
_aMEDICAL / Immunology _2bisacsh |
|
| 650 | 7 |
_aSCIENCE / Physics _2bisacsh |
|
| 700 | 1 |
_aDas, Jayajit, _eeditor. |
|
| 700 | 1 |
_aJayaprakash, Ciriyam, _d1952- _eeditor. |
|
| 856 | 4 | 0 |
_3Taylor & Francis _uhttps://www.taylorfrancis.com/books/e/9781498717410 |
| 856 | 4 | 0 |
_3Taylor & Francis _uhttps://www.taylorfrancis.com/books/9781315119847 |
| 856 | 4 | 2 |
_3OCLC metadata license agreement _uhttp://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf |
| 938 |
_aTaylor & Francis _bTAFR _n9781315119847 |
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| 999 |
_c127851 _d127851 |
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