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001 9780429341441
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008 190830s2019 xx o 000 0 eng d
040 _aOCoLC-P
_beng
_erda
_epn
_cOCoLC-P
020 _a9780429341441
_q(electronic bk.)
020 _a042934144X
_q(electronic bk.)
020 _z9789814800662
020 _a9781000681161
_q(electronic bk. : Mobipocket)
020 _a1000681165
_q(electronic bk. : Mobipocket)
020 _a9781000681437
_q(electronic bk. : EPUB)
020 _a1000681432
_q(electronic bk. : EPUB)
020 _a9781000680898
_q(electronic bk. : PDF)
020 _a1000680894
_q(electronic bk. : PDF)
035 _a(OCoLC)1114600899
_z(OCoLC)1114976756
035 _a(OCoLC-P)1114600899
050 4 _aQP601
072 7 _aMED
_x008000
_2bisacsh
072 7 _aMED
_x009000
_2bisacsh
072 7 _aSCI
_x008000
_2bisacsh
072 7 _aPS
_2bicssc
082 0 4 _a572.7
_223
100 1 _aSuzuki, Haruo,
_d1941-
_eauthor.
245 1 0 _aHow enzymes work :
_bfrom structure to function /
_cHaruo Suzuki.
250 _aSecond edition.
264 1 _a[Place of publication not identified] :
_bJenny Stanford Publishing,
_c2019.
300 _a1 online resource (xiv, 270 pages).
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
505 0 _a1. Overall Reaction Kinetics 2. Facors that Affect Enzyme Activity 3. Effect of pH, Temperature, High pressure on the Enzymatic Activity 4. Measurement of Individual Rate Constants 5. Structure of Protein 6. Cofactors 7. Search of Active site 8. Control of Enzyme Activity 9. Channeling of Substrates and Products10. Preparation of Enzyme 11. A Case Study: L-Phenylalanine Oxidase (Deaminating and Decarboxylating)
520 _aThe first edition of this book covered the basic treatment of the enzyme reaction using the overall reaction kinetics and stopped-flow method, the general properties of protein and cofactors, the control of enzyme reaction, and the preparation of enzyme protein. These topics are the basis of enzyme research and thus suitable for the beginner in the field. The second edition presents the cofactors produced via the post-translational modification of the enzyme's active site. These cofactors expand the function of enzymes and open a new research field. The carbonyl reagent phenylhydrazine and related compounds have been useful in finding some of the newly discovered cofactors and thus have been discussed in this edition. The topic of the control of enzyme activity through the channel of substrates and products in polyfunctional enzymes has also been expanded in this book.
520 8 _aFor a long time, enzymes have been studied by measuring their activity, which has led to the advancement of 'enzyme kinetics'. In recent years, the mechanism of enzyme reaction has been explained in detail on the basis of the 3D structure. Genetic engineering and the 3D structural analysis of enzymes contribute to these advancements in enzymology. This book starts with an introduction to various enzymes to show how interesting enzymes are, which is followed by historical kinetic studies on enzymes and the overall and rapid-reaction kinetics. The subsequent topics describe the basics of protein structure, the control of enzyme activity, and the purification of enzymes.
588 _aOCLC-licensed vendor bibliographic record.
650 7 _aMEDICAL / Biochemistry
_2bisacsh
650 7 _aMEDICAL / Biotechnology
_2bisacsh
650 7 _aSCIENCE / Life Sciences / Biology / General
_2bisacsh
650 0 _aEnzymology.
856 4 0 _3Taylor & Francis
_uhttps://www.taylorfrancis.com/books/9780429341441
856 4 2 _3OCLC metadata license agreement
_uhttp://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf
999 _c126388
_d126388