000			02852nam a22004935i 4500
001			978-88-470-1643-9
003			DE-He213
005			20140220084555.0
007			cr nn 008mamaa
008			101031s2010 it | s |||| 0|eng d
020			_a9788847016439 _9978-88-470-1643-9
024	7		_a10.1007/978-88-470-1643-9 _2doi
050		4	_aRB155.8
072		7	_aMFN _2bicssc
072		7	_aMED107000 _2bisacsh
082	0	4	_a615.895 _223
100	1		_aGiacca, Mauro. _eauthor.
245	1	0	_aGene Therapy _h[electronic resource] / _cby Mauro Giacca.
264		1	_aMilano : _bSpringer Milan, _c2010.
300			_aXXII, 306p. 80 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_ato Gene Therapy -- Therapeutic Nucleic Acids -- Methods for Gene Delivery -- Clinical Applications of Gene Therapy -- Ethical and Social Problems of Gene Therapy.
520			_aThis book presents to the reader a comprehensive and detailed, yet easily accessible, description of the whole field of gene therapy. It covers topics ranging from vector development to the results of the most recent clinical trials. It includes descriptions of lentiviral and AAV vector development, of therapeutic gene selection (including siRNAs, shRNAs, and microRNAs), and of the most recent clinical applications of gene therapy for diseases of the eye, the cardiovascular system, and the central nervous system. Of note, the book only considers conditions for which transfer of genetic material has already progressed to clinical applications or is close to doing so. The language is plain and, whenever possible, non-technical. Since the book is intended to be a textbook in the field of gene therapy in both the basic science and clinical fields, whenever technical descriptions are required these are provided. Readers will include graduate students in the life sciences area in their final years of study, PhD students, and medical doctors specializing in different fields of internal and specialist medicine, in addition to research scientists working in various areas of current biomedical research.
650		0	_aMedicine.
650		0	_aGene therapy.
650		0	_aMedical virology.
650		0	_aGenetic engineering.
650		0	_aInternal medicine.
650	1	4	_aBiomedicine.
650	2	4	_aGene Therapy.
650	2	4	_aMolecular Medicine.
650	2	4	_aInternal Medicine.
650	2	4	_aGenetic Engineering.
650	2	4	_aVirology.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9788847016422
856	4	0	_uhttp://dx.doi.org/10.1007/978-88-470-1643-9
912			_aZDB-2-SBL
999			_c113161 _d113161