000 03314nam a22005295i 4500
001 978-3-642-14153-9
003 DE-He213
005 20140220084541.0
007 cr nn 008mamaa
008 100917s2010 gw | s |||| 0|eng d
020 _a9783642141539
_9978-3-642-14153-9
024 7 _a10.1007/978-3-642-14153-9
_2doi
050 4 _aRB155-155.8
050 4 _aQH431
072 7 _aMFN
_2bicssc
072 7 _aMED107000
_2bisacsh
082 0 4 _a611.01816
_223
082 0 4 _a599.935
_223
100 1 _aMartin, Roland.
_eeditor.
245 1 0 _aMolecular Basis of Multiple Sclerosis
_h[electronic resource] :
_bThe Immune System /
_cedited by Roland Martin, Andreas Lutterotti.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2010.
300 _aVIII, 308 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aResults and Problems in Cell Differentiation,
_x0080-1844 ;
_v51
505 0 _aThe Genetics of Multiple Sclerosis -- Potential Triggers of MS -- Immunological Basis for the Development of Tissue Inflammation and Organ-Specific Autoimmunity in Animal Models of Multiple Sclerosis -- T-Cells in Multiple Sclerosis -- B Cells and Antibodies in MS -- Cooperation of B Cells and T Cells in the Pathogenesis of Multiple Sclerosis -- Role of NK Cells and Invariant NKT Cells in Multiple Sclerosis -- Antigen Processing and Presentation in Multiple Sclerosis -- Immune-Mediated CNS Damage -- Neuro-Immune Crosstalk in CNS Diseases -- Prospects for Antigen-Specific Tolerance Based Therapies for the Treatment of Multiple Sclerosis -- Immuno-Therapeutic Potential of Haematopoietic and Mesenchymal Stem Cell Transplantation in MS -- Multiple Sclerosis Therapies: Molecular Mechanisms and Future -- Examination of the Role of MRI in Multiple Sclerosis: A Problem Orientated Approach.
520 _aDespite major efforts by the scientific community over the years, our understanding of the pathogenesis or the mechanisms of injury of multiple sclerosis is still limited. Consequently, the current strategies for treatment and management of patients are limited in their efficacy. The mechanisms of tissue protection and repair are probably even less understood. One reason for these limitations is the enormous complexity of the disease and every facet of its pathogenesis, the mechanisms of tissue injury, the diagnostic procedures and finally the efficacy of treatments and their side effects. The aim of this book is to review the most recent advances made in this highly complex field.
650 0 _aMedicine.
650 0 _aHuman genetics.
650 0 _aImmunology.
650 0 _aCytology.
650 1 4 _aBiomedicine.
650 2 4 _aHuman Genetics.
650 2 4 _aCell Biology.
650 2 4 _aMolecular Medicine.
650 2 4 _aImmunology.
700 1 _aLutterotti, Andreas.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642141522
830 0 _aResults and Problems in Cell Differentiation,
_x0080-1844 ;
_v51
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-14153-9
912 _aZDB-2-SBL
999 _c112418
_d112418