000 03008nam a22004575i 4500
001 978-3-642-12453-2
003 DE-He213
005 20140220084535.0
007 cr nn 008mamaa
008 100803s2010 gw | s |||| 0|eng d
020 _a9783642124532
_9978-3-642-12453-2
024 7 _a10.1007/978-3-642-12453-2
_2doi
050 4 _aQR1-502
072 7 _aPSG
_2bicssc
072 7 _aSCI045000
_2bisacsh
082 0 4 _a579
_223
100 1 _aHamano, Yoshimitsu.
_eeditor.
245 1 0 _aAmino-Acid Homopolymers Occurring in Nature
_h[electronic resource] /
_cedited by Yoshimitsu Hamano.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2010.
300 _aVII, 250p. 62 illus.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMicrobiology Monographs,
_x1862-5576 ;
_v15
505 0 _aOccurrence and Production of Poly-Epsilon-l-Lysine in Microorganisms -- Biochemistry and Enzymology of Poly-Epsilon-l-Lysine Biosynthesis -- Biochemistry and Enzymology of Poly-Epsilon-l-Lysine Degradation -- Biotechnological Production of Poly-Epsilon-l-Lysine for Food and Medical Applications -- Occurrence and Biosynthetic Mechanism of Poly-Gamma-Glutamic Acid -- Enzymatic Degradation of Poly-Gamma-Glutamic Acid -- Pharmaceutical and Medical Applications of Poly-Gamma-Glutamic Acid -- Food Applications of Poly-Gamma-Glutamic Acid.
520 _aMicroorganisms are capable of producing a wide variety of biopolymers. Homopolymer peptides, which are made up of only a single type of amino acid, are far less ubiquitous. The only two amino-acid homopolymers known to occur in nature are presented in this volume. Poly-epsilon-L-lysine is a polycationic peptide and exhibits antimicrobial activity against a wide spectrum of microorganisms. It is both safe and biodegradable and is therefore used as a food preservative in several countries. In addition, there has been great interest in medical and other applications of poly-lysine and its derivatives. In contrast, poly-gamma-glutamic acid is an unusual anionic polypeptide. It is also water soluble, biodegradable, edible, non-toxic and non-immunogenic and can be chemically modified to introduce various drugs. These features are very useful for pharmaceutical and biomedical applications. Poly-glutamic acid is also a highly attractive as food ingredient.
650 0 _aLife sciences.
650 0 _aBiochemistry.
650 0 _aMicrobiology.
650 1 4 _aLife Sciences.
650 2 4 _aMicrobiology.
650 2 4 _aBiochemistry, general.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642124525
830 0 _aMicrobiology Monographs,
_x1862-5576 ;
_v15
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-12453-2
912 _aZDB-2-SBL
999 _c112081
_d112081