000 03716nam a22004935i 4500
001 978-3-642-12445-7
003 DE-He213
005 20140220084535.0
007 cr nn 008mamaa
008 100623s2010 gw | s |||| 0|eng d
020 _a9783642124457
_9978-3-642-12445-7
024 7 _a10.1007/978-3-642-12445-7
_2doi
050 4 _aQD71-142
072 7 _aPNFC
_2bicssc
072 7 _aSCI013010
_2bisacsh
082 0 4 _a543.8
_223
100 1 _aBerthod, Alain.
_eeditor.
245 1 0 _aChiral Recognition in Separation Methods
_h[electronic resource] :
_bMechanisms and Applications /
_cedited by Alain Berthod.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2010.
300 _aXV, 337p. 155 illus., 15 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aChiral Recognition Mechanisms in Enantiomers Separations: A General View -- Preparation and Chiral Recognition of Polysaccharide-Based Selectors -- Description and Evaluation of Chiral Interactive Sites on Bonded Cyclodextrin Stationary Phases for Liquid Chromatography -- Cyclofructans, a New Class of Chiral Stationary Phases -- Chiral Recognition and Enantioseparation Mechanisms in Capillary Electrokinetic Chromatography -- Chiral Recognition Mechanism: Practical Considerations for Pharmaceutical Analysis of Chiral Compounds -- Chiral Recognition with Macrocyclic Glycopeptides: Mechanisms and Applications -- Vancomycin Molecular Interactions: Antibiotic and Enantioselective Mechanisms -- Enantioselective Recognition in Solution: The Case of Countercurrent Chromatography -- Enantioselective Properties of Nucleic Acid Aptamer Molecular Recognition Elements -- Chiral Ionic Liquids in Chromatographic Separation and Spectroscopic Discrimination.
520 _aThe importance of chiral interactions for both preparative and analytical separations, particularly for pharmaceutical applications, is underlined by numerous publications in this field. Here, for the first time, a team of experienced analysts from industry and academe presents a comprehensive review of the various mechanisms that result in enantiomer separations. A better understanding of these processes is crucial for setting as well as improving chiral separation procedures and also for developing new applications. The coverage in this book includes a range of separation methods, such as gas, liquid, or countercurrent chromatography, and capillary electrophoresis. The special case of chiral ionic liquids is examined in detail. Most modern chiral selectors are discussed, including derivatized polysaccharide- and cyclodextrin-based selectors, along with a newly introduced class of carbohydrates: the cyclofructose selectors. This publication will be required reading not only for research and development departments in the pharmaceutical and cosmetic industries, but also for researchers in toxicology, environmental monitoring, and food research.
650 0 _aChemistry.
650 0 _aToxicology.
650 0 _aChromatography.
650 0 _aFood science.
650 0 _aPharmacy.
650 1 4 _aChemistry.
650 2 4 _aChromatography.
650 2 4 _aPharmacy.
650 2 4 _aPharmacology/Toxicology.
650 2 4 _aFood Science.
650 2 4 _aEnvironmental Monitoring/Analysis.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642124440
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-12445-7
912 _aZDB-2-CMS
999 _c112079
_d112079