000 02854nam a22004695i 4500
001 978-3-642-11836-4
003 DE-He213
005 20140220084532.0
007 cr nn 008mamaa
008 110414s2010 gw | s |||| 0|eng d
020 _a9783642118364
_9978-3-642-11836-4
024 7 _a10.1007/978-3-642-11836-4
_2doi
050 4 _aQH573-671
072 7 _aPSF
_2bicssc
072 7 _aSCI049000
_2bisacsh
082 0 4 _a571.6
_223
100 1 _aRehfeld, Jens F.
_eeditor.
245 1 0 _aCellular Peptide Hormone Synthesis and Secretory Pathways
_h[electronic resource] /
_cedited by Jens F. Rehfeld, Jens R. Bundgaard.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2010.
300 _aX, 8p. 36 illus.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aResults and Problems in Cell Differentiation,
_x0080-1844 ;
_v50
505 0 _aVIP and PACAP -- Biosynthesis of Cardiac Natriuretic Peptides -- Chromogranins A and B and Secretogranin II as Prohormones for Regulatory Peptides from the Diffuse Neuroendocrine System -- Neurotensin and Neuromedin N Are Differentially Processed from a Common Precursor by Prohormone Convertases in Tissues and Cell Lines -- Ghrelin: From Gene to Physiological Function -- Somatostatin and Somatostatin Receptors -- ACTH: Cellular Peptide Hormone Synthesis and Secretory Pathways -- Maturation of Secretory Granules -- Cell-Specific Precursor Processing -- Posttranslational Processing of Progastrin -- Glucagon and Glucagon-Like Peptides 1 and 2.
520 _aThe purpose of the present volume is to illustrate the modern biological concept of basic endocrinology in one single book. It first describes general issues such as maturation of secretory granules in the cells, the roles of the chaperonic granins, and cell-specific prohormone processing. Subsequently, the specific part of the book illustrates the new endocrine biology, using as examples a broad variety of individual peptide systems: ACTH, Neurotensin and Neuromedines, Natriuretic Peptides, Glucagon and Glucagon-like peptides, Somatostatin, Ghrelin, Gastrin and VIP (Vasoactive Intestinal Polypeptide).
650 0 _aLife sciences.
650 0 _aBiochemistry.
650 0 _aCytology.
650 1 4 _aLife Sciences.
650 2 4 _aCell Biology.
650 2 4 _aBiochemistry, general.
700 1 _aBundgaard, Jens R.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642118340
830 0 _aResults and Problems in Cell Differentiation,
_x0080-1844 ;
_v50
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-11836-4
912 _aZDB-2-SBL
999 _c111948
_d111948