000 04265nam a22004455i 4500
001 978-3-642-05080-0
003 DE-He213
005 20140220084527.0
007 cr nn 008mamaa
008 100803s2010 gw | s |||| 0|eng d
020 _a9783642050800
_9978-3-642-05080-0
024 7 _a10.1007/978-3-642-05080-0
_2doi
050 4 _aRB155-155.8
050 4 _aQH431
072 7 _aMFN
_2bicssc
072 7 _aMED107000
_2bisacsh
082 0 4 _a611.01816
_223
082 0 4 _a599.935
_223
100 1 _aTeebi, Ahmad S.
_eeditor.
245 1 0 _aGenetic Disorders Among Arab Populations
_h[electronic resource] /
_cedited by Ahmad S. Teebi.
250 _a2.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2010.
300 _aXII, 600p. 61 illus.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aIntroduction: Genetic Diversity Among Arabs -- Demography, Economy, and Genetic Services in Arab Countries -- Arab Demography and Health Provision -- Influences of Systems’ Resources and Health Risk Factors on Genetic Services -- Endogamy and Consanguineous Marriage in Arab Populations -- Selected Disease Entities Prevalent Among the Arabs -- Familial Mediterranean Fever and Other Autoinflammatory Disorders -- Muscular Dystrophies and Myopathies in Arab Populations -- New Syndromes First Reported Among Arabs -- Genetic disorders in Arab Countries & Geographic Regions -- Genetic Disorders in Egypt -- Genetic Disorders in Ancient Egypt -- Genetic Diseases in Iraq -- Genetic Disorders in Jordan -- Genetic Disorders in Kuwait -- Genetic Disorders in Lebanon -- Genetic Disorders in Libya -- Genetic Disorders in Morocco -- Genetic Disorders in Oman -- Genetic Disorders Among the Palestinians -- Genetic Disorders in Qatar -- Genetic Disorders in Saudi Arabia -- Genetic Disorders in Sudan -- Genetic Disorders in Tunisia -- Genetic Disorders in the United Arab Emirates -- Genetic Disorders Among Jews from Arab Countries -- Cultural and Religious Attitudes Towards Genetic Issues -- Prevention and Care of Genetic Disorders: An Islamic Perspective -- Genetic Counseling in the Middle East.
520 _aArab populations have their “own” genetic disorders, both universal and particular. Genetic diversity within these source populations, along with the fact that the rates of inbreeding are often high and family sizes are often large, constitute conditions that facilitate the emergence and detection of phenotypes explained notably by autosomal recessive inheritance; in which case, the use of homozygosity gene mapping can facilitate the discovery of the corresponding genes. The present book includes 5 parts dealing with various aspects that relate to the genetic structure of Arabs and minorities within the Arab world as well as genetic disorders prevalent in this part of the world. It includes updated reviews of the genetic disorders in various Arab countries and geographic regions. The focus is primarily, but not exclusively, on the group of single-gene disorders with particular emphasis on autosomal recessive conditions. It further includes epidemiological and clinical data as well as inheritance patterns, mutation and polymorphism data, and available haplotype analysis data. The ethnic and genetic diversity of the Arab populations is discussed as well as aspects of genetic counseling practice in this region together with a proposal for an ethical framework for genetic research and prevention of genetic disorders. The target audience of this book includes human and medical geneticists, genetic counselors, researchers, medical specialists dealing with Arab patients or practicing in Arab countries, medical and genetic counseling students, and nurses.
650 0 _aMedicine.
650 0 _aHuman genetics.
650 1 4 _aBiomedicine.
650 2 4 _aHuman Genetics.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642050794
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-05080-0
912 _aZDB-2-SBL
999 _c111673
_d111673