000 03842nam a22005295i 4500
001 978-3-642-04702-2
003 DE-He213
005 20140220084527.0
007 cr nn 008mamaa
008 100917s2010 gw | s |||| 0|eng d
020 _a9783642047022
_9978-3-642-04702-2
024 7 _a10.1007/978-3-642-04702-2
_2doi
050 4 _aQD71-142
072 7 _aPNF
_2bicssc
072 7 _aSCI013010
_2bisacsh
082 0 4 _a543
_223
100 1 _aDemchenko, Alexander P.
_eeditor.
245 1 0 _aAdvanced Fluorescence Reporters in Chemistry and Biology I
_h[electronic resource] :
_bFundamentals and Molecular Design /
_cedited by Alexander P. Demchenko.
246 3 _aWith contributions by numerous experts
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2010.
300 _aX, 390 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringer Series on Fluorescence, Methods and Applications,
_x1617-1306 ;
_v8
505 0 _aGeneral Aspects -- Comparative Analysis of Fluorescence Reporter Signals Based on Intensity, Anisotropy, Time-Resolution, and Wavelength-Ratiometry -- Design of Organic Dyes -- Optimized UV/Visible Fluorescent Markers -- Long-Wavelength Probes and Labels Based on Cyanines and Squaraines -- Two-Photon Absorption in Near-IR Conjugated Molecules: Design Strategy and Structure–Property Relations -- Discovery of New Fluorescent Dyes: Targeted Synthesis or Combinatorial Approach? -- Organic Dyes with Response Function -- Physical Principles Behind Spectroscopic Response of Organic Fluorophores to Intermolecular Interactions -- Organic Dyes with Excited-State Transformations (Electron, Charge, and Proton Transfers) -- Dyes with Segmental Mobility: Molecular Rotors -- Electrochromism and Solvatochromism in Fluorescence Response of Organic Dyes: A Nanoscopic View -- Electric Field Sensitive Dyes -- Fluorophores of visible Fluorescent Proteins -- Photophysics and Spectroscopy of Fluorophores in the Green Fluorescent Protein Family.
520 _aThis volume is focused on one of the most important challenges in sensing and imaging technologies: the design of fluorescence reporters with advanced properties. Here organic dyes occupy leading positions, in tough competition with novel materials such as metal chelating complexes and semiconductor nanoparticles. 11 chapters written by top experts in the field show new possibilities in the design of organic dyes as fluorescent labels and reporters. They particularly highlight the progress that has been made in enhancing the response to intermolecular interactions and their excited-state reaction dynamics (intramolecular charge and proton transfers), and on the development of dyes with strong two-photon absorption and emitting in the near-IR region. Furthermore, fluorophores incorporated into new members of the green fluorescent protein family, an invaluable tool for live cell imaging, are examined.
650 0 _aChemistry.
650 0 _aMedicine.
650 0 _aAnalytical biochemistry.
650 0 _aBiochemistry.
650 0 _aOptical materials.
650 1 4 _aChemistry.
650 2 4 _aAnalytical Chemistry.
650 2 4 _aMolecular Medicine.
650 2 4 _aMedical Biochemistry.
650 2 4 _aBiophysics and Biological Physics.
650 2 4 _aOptical and Electronic Materials.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642047008
830 0 _aSpringer Series on Fluorescence, Methods and Applications,
_x1617-1306 ;
_v8
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-04702-2
912 _aZDB-2-CMS
999 _c111631
_d111631