000 04001nam a22005535i 4500
001 978-3-642-01653-0
003 DE-He213
005 20140220084522.0
007 cr nn 008mamaa
008 100715s2010 gw | s |||| 0|eng d
020 _a9783642016530
_9978-3-642-01653-0
024 7 _a10.1007/978-3-642-01653-0
_2doi
050 4 _aRC902-918
072 7 _aMJR
_2bicssc
072 7 _aMED055000
_2bisacsh
082 0 4 _a616.61
_223
100 1 _aDharnidharka, Vikas R.
_eeditor.
245 1 0 _aPost-Transplant Lymphoproliferative Disorders
_h[electronic resource] /
_cedited by Vikas R. Dharnidharka, Michael Green, Steven A. Webber.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2010.
300 _bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aHistorical Perspective on the Early Studies of Posttransplant Lymphoproliferative Disorders (PTLD) -- Epidemiology of PTLD -- The Biology of Epstein—Barr Virus and Posttransplant Lymphoproliferative Disease -- Epstein—Barr Viral Load Testing: Role in the Prevention, Diagnosis and Management of Posttransplant Lymphoproliferative Disorders -- Clinical Features and Diagnostic Evaluation of Posttransplant Lymphoproliferative Disorder -- Pathology -- Prognostic Factors for PTLD -- Treatment of PTLD -- Prevention of Epstein—Barr Virus Infection and Posttransplant Lymphoproliferative Disease Following Transplantation -- Organ Specific Issues of PTLD — Kidney -- Posttransplantation Lymphoproliferative Disorder (PTLD) in Liver and Small Bowel Transplant Recipients -- Heart and Lung Transplantation -- Posttransplant Lymphoproliferative Disease (PTLD) in Hematopoietic Stem Cell Transplantation (HSCT) -- Research Priorities and Future Directions.
520 _aPost-transplant lymphoproliferative disorders are a group of conditions that straddle the borders between infection and malignancy. They were very rare prior to the mid-1980s but now can be expected to develop in 1-10% of transplant recipients. While some cases are reversible with reduction in immunosuppression, more severe forms are indistinguishable from frank lymphomas. This book sets out to cover in depth every aspect of these disorders, including both basic science and clinical topics. The epidemiology is reviewed, and careful attention is paid to the role of Epstein-Barr virus in their development. Clinical features are documented and clear guidance is provided on diagnosis, with thorough description of pathologic and imaging findings. Further chapters are devoted to treatment, prognosis, preventive and pre-emptive strategies, and organ-specific considerations. The state-of-the-art information contained in this book will aid researchers as well as the many different professionals involved in caring for patients with post-transplant lymphoproliferative disorders. The comprehensive and detailed coverage will appeal to those who already have some expertise in the field, yet the book will also serve as an invaluable resource for beginners in transplantation.
650 0 _aMedicine.
650 0 _aEmerging infectious diseases.
650 0 _aNephrology.
650 0 _aOncology.
650 0 _aHeart
_xSurgery.
650 0 _aSurgery.
650 0 _aTransplantation of organs, tissues, etc.
650 1 4 _aMedicine & Public Health.
650 2 4 _aNephrology.
650 2 4 _aTransplant Surgery.
650 2 4 _aOncology.
650 2 4 _aGeneral Surgery.
650 2 4 _aCardiac Surgery.
650 2 4 _aInfectious Diseases.
700 1 _aGreen, Michael.
_eeditor.
700 1 _aWebber, Steven A.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642016523
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-01653-0
912 _aZDB-2-SME
999 _c111367
_d111367