000 04280nam a22005175i 4500
001 978-3-540-69361-1
003 DE-He213
005 20140220084519.0
007 cr nn 008mamaa
008 100326s2010 gw | s |||| 0|eng d
020 _a9783540693611
_9978-3-540-69361-1
024 7 _a10.1007/978-3-540-69361-1
_2doi
050 4 _aRL1-803
072 7 _aMJK
_2bicssc
072 7 _aMED017000
_2bisacsh
082 0 4 _a616.5
_223
100 1 _aPicardo, Mauro.
_eeditor.
245 1 0 _aVitiligo
_h[electronic resource] /
_cedited by Mauro Picardo, Alain Taïeb.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2010.
300 _bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aDefining the Disease -- Historical Aspects -- Epidemiology, Definitions and Classification -- Histopathology -- Generalized Vitiligo -- Segmental Vitiligo -- Vitiligo Universalis -- Mucosal Vitiligo -- Halo Nevi and Vitiligo -- Hair Involvement in Vitiligo -- Non-Skin Melanocytes in Vitiligo -- Autoimmune/Inflammatory and Other Diseases Associated with Vitiligo -- Vitiligo and Immunodeficiencies -- Inflammatory Vitiligo -- Rare Inherited Diseases and Vitiligo -- Vitiligo in Childhood -- Late-Onset Vitiligo -- Evaluation, Assessment and Scoring -- Quality of Life -- Natural History and Prognosis -- Defining the Disease: Editor's Synthesis -- Understanding the Disease -- Pathophysiology Overview -- Genetics -- Environmental Factors -- In Vivo Data -- Animal Models -- In Vitro Approaches -- Oxidative Stress -- Immune/Inflammatory Aspects -- Cytokines and Growth Factors -- Proopiomelanocortin and Related Hormones -- Other Hypotheses -- Particular Clinical Characteristics of Segmental Vitiligo -- The Concept of Mosaicism Applied to SV -- The Neurogenic Hypothesis in Segmental Vitiligo -- Segmental Vitiligo: A Model for Understanding the Recapitulation of Repigmentation -- Editor’s Synthesis -- Therapy -- Management Overview -- Topical Corticosteroids -- Calcineurin Inhibitors -- Vitamin D Analogues -- PUVA and Related Treatments -- UVB Total Body and Targeted Phototherapies -- Vitamins and Antioxidants: Topical and Systemic -- Corticosteroid Minipulses -- Other Immunosuppressive Regimen -- Empirical, Traditional, and Alternative Treatments -- Background and Techniques -- The Outcomes: Lessons About Surgical Therapy for Vitiligo in the Past Two Decades -- Combined Therapies for Vitiligo -- Camouflage -- Photoprotection Issues -- Depigmenting Agents -- Therapy Adapted for Age, Gender, and Specific Locations -- Psychological Interventions -- The Patient Perspective -- Evidence-Based Medicine Perspective -- Editor's Synthesis and Perspectives.
520 _aVitiligo is one of the most common cutaneous disorders. Great numbers of affected patients suffer from the high stigmatizing impact of this disease. Up to now, clinical guidelines for the treatment of vitiligo were non-existent. In order to fill this void, this textbook defines and gives a complete overview of the disease, both regarding the classification of differential diagnosis as well as the treatment. Written by the most authoritative experts in the field, all therapy recommendations are based on new evidence-based guidelines. It includes case studies with illustrations before and after the treatment in order to demonstrate the treatment success. This textbook will be a valuable resource for all physicians who are seeing patients with this disease.
650 0 _aMedicine.
650 0 _aHuman genetics.
650 0 _aDermatology.
650 0 _aInternal medicine.
650 0 _aSurgery.
650 0 _aCytology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aDermatology.
650 2 4 _aInternal Medicine.
650 2 4 _aPlastic Surgery.
650 2 4 _aHuman Genetics.
650 2 4 _aCell Biology.
700 1 _aTaïeb, Alain.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783540693604
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-540-69361-1
912 _aZDB-2-SME
999 _c111195
_d111195