000 03239nam a22005535i 4500
001 978-3-540-69264-5
003 DE-He213
005 20140220084519.0
007 cr nn 008mamaa
008 100715s2010 gw | s |||| 0|eng d
020 _a9783540692645
_9978-3-540-69264-5
024 7 _a10.1007/978-3-540-69264-5
_2doi
050 4 _aRB155-155.8
050 4 _aQH431
072 7 _aMFN
_2bicssc
072 7 _aMED107000
_2bisacsh
082 0 4 _a611.01816
_223
082 0 4 _a599.935
_223
100 1 _aLin, Shili.
_eauthor.
245 1 0 _aHandbook on Analyzing Human Genetic Data
_h[electronic resource] :
_bComputational Approaches and Software /
_cby Shili Lin, Hongyu Zhao.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2010.
300 _bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aPopulation Genetics -- Haplotype Structure -- Linkage Analysis of Qualitative Traits -- Linkage Analysis of Quantitative Traits -- Markov Chain Monte Carlo Linkage Analysis Methods -- Population-Based Association Studies -- Family-Based Association Studies -- Haplotype Association Analysis -- Multiple Comparisons/Testing Issues -- Estimating the Absolute Risk of Disease Associated with Identified Mutations -- Processing Large-Scale, High-Dimension Genetic and Gene Expression Data.
520 _aThe discipline of statistical genetics is highly computational. Be it exact computational methods, simulation based, or a hybrid of the two, computational packages are indispensable tools and constant companions of researchers in the field. This handbook is intended to provide human geneticists and other biomedical researchers with guidance on selections of appropriate computational methods and software packages for their specific genetic problems. It may also be used by students and other learners as a reference in conjunction with a more theoretical and/or methodologically oriented text book. This book tries to strike a balance between methodological expositions and practical guidelines for software selections. Wherever possible, comparisons among competing methods and software are made to highlight the relative advantages and disadvantage of the approaches so that the readers can make informed choices to best match their specific needs.
650 0 _aMedicine.
650 0 _aHuman genetics.
650 0 _aBioinformatics.
650 0 _aGenetics
_xMathematics.
650 0 _aMathematical statistics.
650 0 _aStatistics.
650 1 4 _aBiomedicine.
650 2 4 _aHuman Genetics.
650 2 4 _aStatistics for Life Sciences, Medicine, Health Sciences.
650 2 4 _aBioinformatics.
650 2 4 _aComputational Biology/Bioinformatics.
650 2 4 _aGenetics and Population Dynamics.
650 2 4 _aStatistical Theory and Methods.
700 1 _aZhao, Hongyu.
_eauthor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783540692638
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-540-69264-5
912 _aZDB-2-SBL
999 _c111194
_d111194