000 03800nam a22005535i 4500
001 978-1-84882-822-3
003 DE-He213
005 20140220084514.0
007 cr nn 008mamaa
008 100316s2010 xxk| s |||| 0|eng d
020 _a9781848828223
_9978-1-84882-822-3
024 7 _a10.1007/978-1-84882-822-3
_2doi
050 4 _aRB112.5
072 7 _aPSB
_2bicssc
072 7 _aMED008000
_2bisacsh
082 0 4 _a612.015
_223
100 1 _aBronner, Felix.
_eeditor.
245 1 0 _aBone and Development
_h[electronic resource] /
_cedited by Felix Bronner, Mary C. Farach-Carson, H.I (Trudy) Roach.
264 1 _aLondon :
_bSpringer London,
_c2010.
300 _aXII, 300p. 66 illus., 44 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aTopics in Bone Biology ;
_v6
505 0 _aGenetic and Epigenetic Aspects of Bone Development -- Tissue Interactions in Long Bone Development -- The Epiphyseal Growth Plate -- Hedgehog Signaling in Growth Plate and Bone Development -- Role of microRNA in Skeleton Development -- FGF/FGFR Signaling in Skeletal Dysplasias -- The Role of Hypoxia-Induced Factors -- BMP Signaling in Skeletogenesis -- Wnt Signaling in Bone Development -- Development of the Craniofacial Complex -- Dentin and Bone: Similar Collagenous Mineralized Tissues -- Evolution of Bone Proteins -- Osteogenesis Imperfecta -- Fibrodysplasia Ossificans Progressiva: Developmental Implications of a Novel Metamorphogene -- Bone-Mineral Homeostasis and Associated Pathologies -- Interrelationship Between Bone and Other Tissues: Brain–Bone Axis and Bone-Adipo Axis -- Mechanobiology of Bone Development and Computational Simulations.
520 _aThis volume, the sixth in the series Topics in Bone Biology, presents the current knowledge of bone development, from growth to mineralization. Like previous volumes in this series, it embraces the important interaction between medical science and practice. Insights stemming from molecular and cellular events are applied to the clinical setting, providing a deeper understanding of bone development complications for the practicing clinician, whilst informing bone scientists of the advancements in their field and the wider applications of their research. Covering a diverse and current range of topics, including the genetic and epigenetic aspects of bone development, cell signaling in growth plate and bone development, evolution of bone proteins and the interrelationship between bone and other tissues, this volume provides a thorough look at bone development biology. The contributing authors to this volume are acknowledged authorities in their fields. In addition, the extensive lists of references point the reader to further information on any of the topics covered. Clinicians and researchers involved in child development and therapy will find this book a valuable addition to their libraries.
650 0 _aMedicine.
650 0 _aInternal medicine.
650 0 _aBiochemistry.
650 0 _aOrthopedics.
650 0 _aPediatrics.
650 0 _aRheumatology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aMedical Biochemistry.
650 2 4 _aOrthopedics.
650 2 4 _aPediatrics.
650 2 4 _aRheumatology.
650 2 4 _aInternal Medicine.
700 1 _aFarach-Carson, Mary C.
_eeditor.
700 1 _aRoach, H.I (Trudy).
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781848828216
830 0 _aTopics in Bone Biology ;
_v6
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-84882-822-3
912 _aZDB-2-SME
999 _c110901
_d110901