000 03680nam a22005175i 4500
001 978-1-60761-775-4
003 DE-He213
005 20140220084513.0
007 cr nn 008mamaa
008 100803s2010 xxu| s |||| 0|eng d
020 _a9781607617754
_9978-1-60761-775-4
024 7 _a10.1007/978-1-60761-775-4
_2doi
050 4 _aQH588.S83
072 7 _aPSAK
_2bicssc
072 7 _aSCI017000
_2bisacsh
072 7 _aSCI049000
_2bisacsh
082 0 4 _a571.6
_223
100 1 _aRojas, Mauricio.
_eeditor.
245 1 0 _aStem Cells in the Respiratory System
_h[electronic resource] /
_cedited by Mauricio Rojas.
264 1 _aTotowa, NJ :
_bHumana Press :
_bImprint: Humana Press,
_c2010.
300 _aX, 170 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aStem Cell Biology and Regenerative Medicine
505 0 _aStem and Progenitor Cells of the Airway Epithelium -- Mesenchymal Stem Cells for Lung Repair and Regeneration -- The Role of Progenitor Cells in Lung Disease Prognosis -- The Role of Fibrocytes in Lung Repair and Fibrosis -- Stem Cells and Cell–Matrix Interactions in Lung -- Mobilization of Stem Cells/Progenitor Cells by Physical Activity -- Mesenchymal Stem Cells for Acute Lung Injury -- Animal Models of Lung Injury: Role for Mesenchymal Stem Cells.
520 _aIn this state-of-the-art exploration of a hugely dynamic and fast-evolving field of research, leading researchers share their collective wisdom on the role that stem cells could play in the context of physiological stress and lung injury. The text focuses on reviewing the most relevant—and recent—ideas on using local, endogenous, and exogenous progenitor/stem cells in preventing and treating injury to the lung. The lungs are one of the most complex organs in the human body, with a mature adult lung boasting at least 40 morphologically differentiated cell lineages. Our entire blood supply passes through the lung’s alveolar units during oxygenation. This interaction with the outside world, along with the intricacies of its structure, makes the lung a highly susceptible organ that is vulnerable to numerous types of injury and infection. This means that the mechanisms of lung repair are in themselves correspondingly complex. Because of their multipotentiality, as well as the fact of the lung’s relatively rapid cell turnover, stem cells are thought to be an important alternative cell-base therapy in lung injury. Despite the controversial nature of stem cell research, there has been growing interest in both local and endogenous stem cells in the lung. This highly topical book with chapters on everything from using mesenchymal stem cells in lung repair to the effect of physical activity on the mobilization of stem and progenitor cells, represents an exciting body of work by outstanding investigators and will be required reading for those with an interest in the subject.
650 0 _aLife sciences.
650 0 _aOncology.
650 0 _aPneumology.
650 0 _aCytology.
650 0 _aStem cells.
650 1 4 _aLife Sciences.
650 2 4 _aStem Cells.
650 2 4 _aPneumology/Respiratory System.
650 2 4 _aCell Biology.
650 2 4 _aCancer Research.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781607617747
830 0 _aStem Cell Biology and Regenerative Medicine
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-60761-775-4
912 _aZDB-2-SBL
999 _c110834
_d110834