000 02737nam a22004455i 4500
001 978-1-4419-8056-4
003 DE-He213
005 20140220084512.0
007 cr nn 008mamaa
008 110628s2010 xxu| s |||| 0|eng d
020 _a9781441980564
_9978-1-4419-8056-4
024 7 _a10.1007/978-1-4419-8056-4
_2doi
050 4 _aR-RZ
072 7 _aMBGR
_2bicssc
072 7 _aMED000000
_2bisacsh
082 0 4 _a610
_223
100 1 _aThurmond, Robin L.
_eeditor.
245 1 0 _aHistamine in Inflammation
_h[electronic resource] /
_cedited by Robin L. Thurmond.
264 1 _aBoston, MA :
_bSpringer US,
_c2010.
300 _aXVIII, 143 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v709
505 0 _aOne Hundred Years of Histamine Research -- Molecular Pharmacology of the Four Histamine Receptors -- Histamine Synthesis and Lessons Learned from Histidine Decarboxylase Deficient Mice -- Histamine in Allergic Rhinitis -- The Role of Histamine in Ocular Allergy -- The Role of Histamine in Asthma -- Antihistamines in the Treatment of Urticaria -- Histamine and Antihistamines in Atopic Dermatitis -- Histamine, Immune Cells and Autoimmunity -- Histamine in Neurotransmission and Brain Diseases -- Histamine in Normal and Malignant Cell Proliferation -- The Future Antihistamines: Histamine H3 and H4 Receptor Ligands.
520 _aThe year 2010 marks the centennial for the identification of histamine and the first glimpse of its many physiological functions. From these initial findings a rich tapestry of research has uncovered roles for histamine in almost every physiological process with new findings emerging every year. These diverse roles of histamine have made for fertile ground for the discovery of novel therapeutics, and these drugs have been so successful that the term “antihistamine” has entered the common lexicon. This book is an attempt to give a snapshot in time as to the current understanding of the role of histamine in just one important therapeutic area—inflammation.
650 0 _aMedicine.
650 0 _aHuman physiology.
650 1 4 _aBiomedicine.
650 2 4 _aBiomedicine general.
650 2 4 _aHuman Physiology.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781441980557
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v709
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4419-8056-4
912 _aZDB-2-SBL
999 _c110757
_d110757