000 03025nam a22004455i 4500
001 978-1-4419-7913-1
003 DE-He213
005 20140220084511.0
007 cr nn 008mamaa
008 110625s2010 xxu| s |||| 0|eng d
020 _a9781441979131
_9978-1-4419-7913-1
024 7 _a10.1007/978-1-4419-7913-1
_2doi
050 4 _aR-RZ
072 7 _aMBGR
_2bicssc
072 7 _aMED000000
_2bisacsh
082 0 4 _a610
_223
100 1 _aYona, Simon.
_eeditor.
245 1 0 _aAdhesion-GPCRs
_h[electronic resource] :
_bStructure to Function /
_cedited by Simon Yona, Martin Stacey.
264 1 _aBoston, MA :
_bSpringer US,
_c2010.
300 _aXXI, 199 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v706
505 0 _aThe Adhesion GPCRs; Gene Repertoire, Phylogeny and Evolution -- 7TM-Cadherins: Developmental Roles and Future Challenges -- Latrophilin Signalling in Tissue Polarity and Morphogenesis -- GPS Proteolytic Cleavage of Adhesion-GPCRs -- The Latrophilins, “Split-Personality” Receptors -- Studies on the Very Large G Protein-Coupled Receptor: From Initial Discovery to Determining its Role in Sensorineural Deafness in Higher Animals -- Adhesion-GPCRs in the CNS -- GPR56 Interacts with Extracellular Matrix and Regulates Cancer Progression -- Adhesion-GPCRs in Tumorigenesis -- Immunity and Adhesion-GPCRs -- CD97 in Leukocyte Trafficking -- The Role of CD97 in Regulating Adaptive T-Cell Responses -- F4/80: The Macrophage-Specific Adhesion-GPCR and its Role in Immunoregulation -- Signal Transduction Mediated through Adhesion-GPCRs -- Emerging Roles of Brain-Specific Angiogenesis Inhibitor 1 -- Adhesion-GPCRs in the Male Reproductive Tract.
520 _aThe field of adhesion‑GPCR biology has indeed become large enough to require a volume dedicated solely to this field. The contributors to this book have made a courageous effort to address the key concepts of adhesion‑GPCR biology, including the evolution and biochemistry of adhesion‑GPCRs; there are extensive discussions on the functional nature of these receptors during development, the immune response and tumourgenesis. Finally, there are chapters dedicated to adhesion‑GPCR signalling, an area of intense investigation. This volume focuses on the recent advances in adhesion‑GPCR biology.
650 0 _aMedicine.
650 1 4 _aBiomedicine.
650 2 4 _aBiomedicine general.
650 2 4 _aMolecular Medicine.
700 1 _aStacey, Martin.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781441979124
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v706
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4419-7913-1
912 _aZDB-2-SBL
999 _c110756
_d110756