000 03106nam a22004575i 4500
001 978-1-4419-6902-6
003 DE-He213
005 20140220084510.0
007 cr nn 008mamaa
008 110112s2010 xxu| s |||| 0|eng d
020 _a9781441969026
_9978-1-4419-6902-6
024 7 _a10.1007/978-1-4419-6902-6
_2doi
050 4 _aR-RZ
072 7 _aMBGR
_2bicssc
072 7 _aMED000000
_2bisacsh
082 0 4 _a610
_223
100 1 _aGeary, Timothy G.
_eeditor.
245 1 0 _aNeuropeptide Systems as Targets for Parasite and Pest Control
_h[electronic resource] /
_cedited by Timothy G. Geary, Aaron G. Maule.
264 1 _aBoston, MA :
_bSpringer US,
_c2010.
300 _aXVIII, 230 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v692
505 0 _aReceptor-Based Discovery Strategies for Insecticides and Parasiticides: A Review -- Nonpeptide Ligands for Peptidergic G Protein-Coupled Receptors -- Interaction of Mimetic Analogs of Insect Kinin Neuropeptides with Arthropod Receptors -- Neuropeptides in Helminths: Occurrence and Distribution -- Neuropeptide Physiology in Helminths -- Neuropeptide Gene Families in Caenorhabditis elegans -- Control of Nematode Parasites with Agents Acting on Neuro-Musculature Systems: Lessons for Neuropeptide Ligand Discovery -- Neuropeptide Signaling in Insects -- Neuropeptide Physiology in Insects -- Neuropeptide Biology in Drosophila -- Neuropeptide Receptors as Possible Targets for Development of Insect Pest Control Agents.
520 _aThis book was assembled to focus attention on this promising field by compiling a comprehensive review of recent research on neuropeptides in arthropods and helminths, with contributions from many of the leading laboratories working on these systems. The organization of the chapters is intended to provide an overview of the organism-level biology of neuropeptidergic function in insects and helminths, progressing to an understanding of the molecular biology of the genes that encode their precursors and receptors in these organisms. We include for perspective consideration of the state of the art in discovery of insecticides and anthelmintics, a review of drugs that affect similar systems in nematodes, and a summary of drug discovery efforts that target mammalian neuropeptide receptors for therapy of non-infectious diseases in humans.
650 0 _aMedicine.
650 0 _aMedical parasitology.
650 1 4 _aBiomedicine.
650 2 4 _aBiomedicine general.
650 2 4 _aParasitology.
700 1 _aMaule, Aaron G.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781441969019
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v692
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4419-6902-6
912 _aZDB-2-SBL
999 _c110704
_d110704