000 03552nam a22004815i 4500
001 978-1-4419-6451-9
003 DE-He213
005 20140220084509.0
007 cr nn 008mamaa
008 110110s2010 xxu| s |||| 0|eng d
020 _a9781441964519
_9978-1-4419-6451-9
024 7 _a10.1007/978-1-4419-6451-9
_2doi
050 4 _aQH506
072 7 _aMBGR
_2bicssc
072 7 _aPSD
_2bicssc
072 7 _aSCI049000
_2bisacsh
072 7 _aMED067000
_2bisacsh
082 0 4 _a611.01816
_223
100 1 _aZanetti, Maurizio.
_eeditor.
245 1 0 _aMemory T Cells
_h[electronic resource] /
_cedited by Maurizio Zanetti, Stephen P. Schoenberger.
264 1 _aNew York, NY :
_bSpringer New York,
_c2010.
300 _aXXIV, 198p. 37 illus., 4 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v684
505 0 _aMemory Th1/Th2 Cell Generation Controlled by Schnurri-2 -- Transcriptional Regulation during CD8 T-Cell Immune Responses -- The Role of Interleukin-2 in Memory CD8 Cell Differentiation -- The Role of Inflammation in the Generation and Maintenance of Memory T Cells -- The Role of OX40 (CD134) in T-Cell Memory Generation -- The Role of Precursor Frequency in the Differentiation of Memory T Cells: Memory by Numbers -- CD8 T-Cell Memory Differentiation during Acute and Chronic Viral Infections -- Longevity of T-Cell Memory following Acute Viral Infection -- Principles of Memory CD8 T-Cells Generation in Relation to Protective Immunity -- Memory T Cells in Rhesus Macaques -- Memory T-Cell Subsets in Parasitic Infections -- Antigen Specific Memory T Cells and Their Putative Need for the Generation of Sustained Anti-Tumor Responses -- Memory T-Cell Responses and Survival in Human Cancer: Remember to Stay Alive -- Analysis of Vaccine-Induced T Cells in Humans with Cancer -- Memory T-Cell Homeostasis and Senescence during Aging.
520 _aImmunological memory has fascinated microbiologists and immunologists for decades as one of the new frontiers to conquer to better understand the response to pathogens, cancer and vaccination. Over the past decade, attention has turned to the intrinsic properties of the memory T cells themselves, as it has become clear that the eradication of both infected cells and tumors requires T cells. This book is an attempt to capture the wave of discoveries associated with these recent studies. Its chapters represent a wide collection of topics related to memory T cells by laboratories that have invested their skills and knowledge to understand the biology and the principles upon which memory T cells are generated, maintained and expanded upon re-encounter with antigen. Ultimately, these studies are all aimed at a better understanding of the function of memory T cells in protection against disease.
650 0 _aMedicine.
650 0 _aNeurochemistry.
650 1 4 _aBiomedicine.
650 2 4 _aMolecular Medicine.
650 2 4 _aNeurochemistry.
700 1 _aSchoenberger, Stephen P.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781441964502
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v684
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4419-6451-9
912 _aZDB-2-SBL
999 _c110641
_d110641