000			04757nam a22004935i 4500
001			978-1-4419-6324-6
003			DE-He213
005			20140220084509.0
007			cr nn 008mamaa
008			100917s2010 xxu| s |||| 0|eng d
020			_a9781441963246 _9978-1-4419-6324-6
024	7		_a10.1007/978-1-4419-6324-6 _2doi
050		4	_aQH345
050		4	_aQD415-436
072		7	_aPSB _2bicssc
072		7	_aSCI007000 _2bisacsh
082	0	4	_a572 _223
100	1		_aBergethon, Peter R. _eauthor.
245	1	4	_aThe Physical Basis of Biochemistry _h[electronic resource] : _bThe Foundations of Molecular Biophysics / _cby Peter R. Bergethon.
250			_a2.
264		1	_aNew York, NY : _bSpringer New York : _bImprint: Springer, _c2010.
300			_aXXX, 950p. 200 illus. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aPrinciples of Biophysical Inquiry -- Introduction: To the Student – First Edition -- Philosophy and Practice of Biophysical Study -- Overview of the Biological System Under Study -- Physical Thoughts, Biological Systems – The Application of Modeling Principles to Understanding Biological Systems -- Probability and Statistics -- Foundations -- Energy and Force – The Prime Observables -- Biophysical Forces in Molecular Systems -- Physical Principles: Quantum Mechanics -- Chemical Principles -- Measuring the Energy of a System: Energetics and the First Law of Thermodynamics -- Entropy and the Second Law of Thermodynamics -- Which Way Is That System Going? The Gibbs Free Energy -- The Thermodynamics of Phase Equilibria -- Building a Model of Biomolecular Structure -- Water: A Unique Solvent and Vital Component of Life -- Ion–Solvent Interactions -- Ion–Ion Interactions -- Lipids in Aqueous Solution -- Macromolecules in Solution -- Molecular Modeling – Mapping Biochemical State Space -- The Electrified Interphase -- Function and Action Biological State Space -- Transport – A Non-equilibrium Process -- Flow in a Chemical Potential Field: Diffusion -- Flow in an Electric Field: Conduction -- Forces Across Membranes -- Kinetics – Chemical Kinetics -- Dynamic Bioelectrochemistry – Charge Transfer in Biological Systems -- Methods for the Measuring Structure and Function -- Separation and Characterization of Biomolecules Based on Macroscopic Properties -- Analysis of Molecular Structure with Electronic Spectroscopy -- Molecular Structure from Scattering Phenomena -- Analysis of Structure – Microscopy -- Epilogue -- Physical Constants.
520			_aThe Physical Basis of Biochemistry is an introduction to the philosophy and practice of an interdisciplinary field in which biological systems are explored using the quantitative perspective of the physical scientist. As with the first edition, the idea that a fundamental understanding of the basic physical principles underlying chemical biological systems is vital remains the focus of this second edition. This new edition of The Physical Basis of Biochemistry has substantial new material added with respect to models at the simple molecular level (including van der Waals gases and virial treatments) which is tied to coverage of models of polymer thermo-dynamics. The second edition is partitioned into five sections: the central concept that science is a way of looking at the world; the physical under-pinnings of biophysical chemistry with an emphasis first on energy, work and forces of biological importance; exploring how models applicable to molecular biophysics are constructed; the three-dimensional potential energy surface put into motion; and a succinct discussion of the bio-physical methods used to evaluate structure and function in biological systems. Additionally, a section of appendices continues to serve the pur¬pose of presenting some review information and certain topics in detail. The Physical Basis of Biochemistry will be of interest to quantitatively-oriented biologists as well as aspiring chemists, physicists, and engineers with an interest in biological systems.
650		0	_aLife sciences.
650		0	_aMedicine.
650		0	_aChemistry, Physical organic.
650		0	_aBiochemistry.
650	1	4	_aLife Sciences.
650	2	4	_aBiochemistry, general.
650	2	4	_aBiophysics and Biological Physics.
650	2	4	_aPhysical Chemistry.
650	2	4	_aBiomedicine general.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781441963239
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-4419-6324-6
912			_aZDB-2-SBL
999			_c110614 _d110614