000 02884nam a22004695i 4500
001 978-1-4419-6033-7
003 DE-He213
005 20140220084508.0
007 cr nn 008mamaa
008 100623s2010 xxu| s |||| 0|eng d
020 _a9781441960337
_9978-1-4419-6033-7
024 7 _a10.1007/978-1-4419-6033-7
_2doi
050 4 _aRC254-282
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a616.994
_223
100 1 _aPasche, Boris.
_eeditor.
245 1 0 _aCancer Genetics
_h[electronic resource] /
_cedited by Boris Pasche.
264 1 _aBoston, MA :
_bSpringer US :
_bImprint: Springer,
_c2010.
300 _aXII, 112p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aCancer Treatment and Research,
_x0927-3042 ;
_v155
505 0 _aEthicolegal Aspects of Cancer Genetics -- The Influence of Common Polymorphisms on Breast Cancer -- Hereditary Diffuse Gastric Cancer -- Genetics and Genomics of Neuroblastoma -- TGF-? Signaling Alterations and Colon Cancer.
520 _aCancer genetics has revolutionized the practice of medicine as inherited genetic information helps predicts which individuals are at risk of developing various forms of cancer. Furthermore, somatically acquired genetic changes help identify therapeutic targets for patients with several common tumor types such as breast and colon cancer. Cancer Genetics reviews seminal discoveries such as genetic susceptibility to gastric cancer, ethical issues related to cancer genetics, the role of common variants in the development of breast cancer, novel genetic findings related to neuroblastoma, and the role of constitutively decreased TGF-beta signaling, which is emerging as one of the most common causes of colorectal cancer. The book has been written for all clinicians and researchers interested in cancer genetics, including oncologists, genetic counselors and cancer researchers both in academia and in industry. "Genetic alterations are a fundamental component of all cancers. This text highlights critical issues relevant for both basic scientists and clinicians. Recognized thought leaders in the field discuss current knowledge and future challenges." - Steven T. Rosen, M.D., Series Editor
650 0 _aMedicine.
650 0 _aOncology.
650 0 _aHuman genetics.
650 1 4 _aMedicine & Public Health.
650 2 4 _aOncology.
650 2 4 _aCancer Research.
650 2 4 _aHuman Genetics.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781441960320
830 0 _aCancer Treatment and Research,
_x0927-3042 ;
_v155
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4419-6033-7
912 _aZDB-2-SME
999 _c110573
_d110573