000 03890nam a22005535i 4500
001 978-1-4419-1050-9
003 DE-He213
005 20140220084504.0
007 cr nn 008mamaa
008 100301s2010 xxu| s |||| 0|eng d
020 _a9781441910509
_9978-1-4419-1050-9
024 7 _a10.1007/978-1-4419-1050-9
_2doi
050 4 _aQR180-189.5
072 7 _aMJCM
_2bicssc
072 7 _aMED044000
_2bisacsh
082 0 4 _a616.079
_223
100 1 _aChoi, Yongwon.
_eeditor.
245 1 0 _aOsteoimmunology
_h[electronic resource] :
_bInteractions of the Immune and skeletal systems II /
_cedited by Yongwon Choi.
264 1 _aBoston, MA :
_bSpringer US,
_c2010.
300 _bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v658
505 0 _aThe Role of Bone Marrow Edema and Lymphangiogenesis in Inflammatory-Erosive Arthritis -- Activation of ?? T Cells by Bisphosphonates -- Identification of Cell Cycle-Arrested Quiescent Osteoclast Precursors In Vivo -- Megakaryocyte-Bone Cell Interactions -- Regulation of Osteoblast Differentiation by Runx2 -- Communication Between EphrinB2 and EphB4 Within the Osteoblast Lineage -- The Unexpected Link Between Osteoclasts and the Immune System -- NFATc1 in Inflammatory and Musculoskeletal Conditions -- Novel Functions of RANK(L) Signaling in the Immune System -- Eph and Ephrin Interactions in Bone -- How Do Bone Cells Secrete Proteins? -- Regulation of Osteoclast Apoptosis by Bcl-2 Family Protein Bim and Caspase-3 -- Regulation of Bone Formation and Immune Cell Development by Schnurri Proteins.
520 _aIt has only recently been appreciated that the immune and skeletal systems have major interactions. It is now well documented that osteoclasts, which are important cellular mediators of skeletal homeostasis, are derived from hematopoietic precursors that also give rise to immune cells. In addition, numerous cytokines that were first shown to regulate immune cell function have also been demonstrated to regulate bone cells and influence skeletal health. Conversely, products of bone cells appear critical for the engraftment of marrow in bone, the normal development of the hematopoietic and immune systems and provide niche for long-term memory B and T cells. In the past scientists involved in immune and bone cell investigations have rarely interacted in a significant way as these disciplines have developed independently and, for the most part, remain separate. The conference will bring together leading international scientists from both fields to interact so that new collaboration can develop and more rapid progress in understanding the relationships between these fields can be achieved. Short talks will be selected from abstracts from the international community. This conference will have a format to provide an environment of maximum interaction and interchange through lectures, posters, and open discussion.
650 0 _aMedicine.
650 0 _aImmunology.
650 0 _aToxicology.
650 0 _aBiotechnology.
650 0 _aEmerging infectious diseases.
650 0 _aPathology.
650 0 _aMicrobiology.
650 1 4 _aBiomedicine.
650 2 4 _aImmunology.
650 2 4 _aMicrobiology.
650 2 4 _aInfectious Diseases.
650 2 4 _aBiotechnology.
650 2 4 _aPathology.
650 2 4 _aPharmacology/Toxicology.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781441910493
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v658
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4419-1050-9
912 _aZDB-2-SBL
999 _c110304
_d110304