000 02922nam a22004335i 4500
001 978-1-4419-0775-2
003 DE-He213
005 20140220084503.0
007 cr nn 008mamaa
008 100301s2010 xxu| s |||| 0|eng d
020 _a9781441907752
_9978-1-4419-0775-2
024 7 _a10.1007/978-1-4419-0775-2
_2doi
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a614.5999
_223
100 1 _aMyers, Jeffrey.
_eeditor.
245 1 0 _aOral Cancer Metastasis
_h[electronic resource] /
_cedited by Jeffrey Myers.
250 _a1.
264 1 _aNew York, NY :
_bSpringer New York,
_c2010.
300 _bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aOral Cancer Overview: The Significance of Metastasis and Surgical Management of the Neck -- The Role of Diagnostic Imaging in Identifying Cervical Metastases in Oral Cavity Cancer -- Sentinel Node Biopsy in Oral Cancer -- Prediction of Nodal Metastases from Genomic Analyses of the Primary Tumor -- The Role of High Throughput Molecular Analysis of Biofluids and Tumors in Patients with Oral Cancer -- Adjuvant Therapy for Patients with Oral Cavity Cancer -- Animal Models of Oral Cancer Metastasis -- TGF? Signaling in Head and Neck Cancer Development and Metastases -- Growth Factor Receptor Signaling and Metastasis of Oral Cancer -- Nuclear Transcription Factors and Signaling Pathways in Oral Cancer Metastasis -- Wnt/?-Catenin Signaling and Oral Cancer Metastasis -- Role of Tumor Stromal Interactions and Proteases in Oral Cancer Metastasis -- Chemokines and Their Receptors in Oral Cancer Metastasis -- Hypoxia, Angiogenesis, and Oral Cancer Metastasis -- Cancer Stem Cells and Oral Cavity Cancer Metastasis.
520 _aSquamous cell carcinoma of the oral cavity (SCCOC) is one of the most prevalent tumors of the head and neck region. Despite improvements in treatment, the survival of patients with SCCOC has not significantly improved over the past several decades. Most frequently, treatment failure takes the form of local and regional recurrences, but as disease control in these areas improves, SCCOC treatment failures more commonly occur as distant metastasis. This book summarizes the current status of investigations into SCCOC metastases and potential of these studies to positively impact clinical management of SCCOC in the future.
650 0 _aMedicine.
650 0 _aOncology.
650 1 4 _aBiomedicine.
650 2 4 _aCancer Research.
650 2 4 _aOncology.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781441907745
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4419-0775-2
912 _aZDB-2-SBL
999 _c110250
_d110250