000			03479nam a22004455i 4500
001			978-1-4419-0410-2
003			DE-He213
005			20140220084502.0
007			cr nn 008mamaa
008			100301s2010 xxu| s |||| 0|eng d
020			_a9781441904102 _9978-1-4419-0410-2
024	7		_a10.1007/978-1-4419-0410-2 _2doi
050		4	_aRC261-271
072		7	_aMJCL _2bicssc
072		7	_aMED062000 _2bisacsh
082	0	4	_a614.5999 _223
100	1		_aRay, Swapan K. _eeditor.
245	1	0	_aGlioblastoma _h[electronic resource] : _bMolecular Mechanisms of Pathogenesis and Current Therapeutic Strategies / _cedited by Swapan K. Ray.
264		1	_aNew York, NY : _bSpringer New York, _c2010.
300			_aXII, 431p. 49 illus., 18 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aOverview of the Molecular Genetics and Molecular Chemotherapy of GBM -- Primary Brain Tumors: Characteristics, Practical Diagnostic and Treatment Approaches -- Pathology of Glioblastoma Multiforme -- Molecular Mechanisms of Pathogenesis in Glioblastoma and Current Therapeutic Strategies -- Aberrant Signalling Complexes in GBMs: Prognostic and Therapeutic Implications -- Role of Aberrant Cell Cycle in the Growth and Pathogenesis of Glioblastoma -- Adult Neural Stem Cells and Gliomagenesis -- Divide and Invade: The Dynamic Cytoskeleton of Glioblastoma Cells -- Aberrations of the Epigenome in Gliomas: Novel Targets for Therapy -- Chemotherapy for Glioblastoma: Past, Present, and Future -- Role of Angiogenesis in the Pathogenesis of Glioblastoma and Antiangiogenic Therapies for Controlling Glioblastoma -- Antiangiogenic Strategies for the Treatment of Gliomas -- Retinoids for the Treatment of Glioblastoma -- Molecular Mechanisms of Taxol for Induction of Cell Death in Glioblastomas -- Current Endeavors for Enhancing Efficacy of Paclitaxel for Treatment of Glioblastoma -- Dietary Polyphenols as Preventive and Therapeutic Agents in Glioblastoma -- Targeting Energy Metabolism in Brain Cancer with Restricted Diets -- Immunotherapy for Glioblastoma -- Potential of Nanobiotechnology in the Management of Glioblastoma Multiforme.
520			_aGlioblastoma, the deadliest of all primary brain tumors, is heterogenic and has very complex pathology and multiple mechanisms of cell proliferation and growth. This book describes all the latest concepts about the molecular mechanisms of pathogenesis of glioblastoma and new therapeutic opportunities. The contributors to this book include basic scientists and clinicians, who are experts in the field, and dedicated investigators in finding novel strategies for treatment of glioblastoma. It is important for us to know the strategies we have accumulated so far for the management of this malignancy so that we can make further attempts to explore unknown avenues to combat it completely in the near future.
650		0	_aMedicine.
650		0	_aOncology.
650		0	_aNeurosciences.
650	1	4	_aBiomedicine.
650	2	4	_aCancer Research.
650	2	4	_aOncology.
650	2	4	_aNeurosciences.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781441904096
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-4419-0410-2
912			_aZDB-2-SBL
999			_c110197 _d110197